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LOC119402328 dual specificity protein phosphatase 8 [ Rhipicephalus sanguineus (brown dog tick) ]

Gene ID: 119402328, updated on 27-Mar-2024

Summary

Gene symbol
LOC119402328
Gene description
dual specificity protein phosphatase 8
See related
VectorBase:RSAN_032616; EnsemblRapid:LOC119402328
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhipicephalus sanguineus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae; Rhipicephalus; Rhipicephalus
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Genomic context

Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
101 current BIME_Rsan_1.4 (GCF_013339695.2) 8 NC_051183.1 (116379121..116471004)
100 previous assembly ASM1333969v1 (GCF_013339695.1) 8 NC_051183.1 (116379114..116471004)

Chromosome 8 - NC_051183.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein K02A2.6-like Neighboring gene uncharacterized LOC125759489 Neighboring gene venom metalloproteinase antarease-like TtrivMP_A Neighboring gene uncharacterized LOC119403463

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
dual specificity protein phosphatase 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhipicephalus sanguineus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BIME_Rsan_1.4

Genomic

  1. NC_051183.1 Reference BIME_Rsan_1.4

    Range
    116379121..116471004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037669469.2XP_037525397.1  dual specificity protein phosphatase 8 isoform X1

    UniProtKB/TrEMBL
    A0A9D4PG44
    Related
    XP_037525397.1, XM_037669469.2
    Conserved Domains (2) summary
    cd01446
    Location:11131
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14568
    Location:153292
    DSP_MKP_classIII; dual specificity phosphatase domain of class III mitogen-activated protein kinase phosphatase
  2. XM_037669471.2XP_037525399.1  dual specificity protein phosphatase 8 isoform X2

    UniProtKB/TrEMBL
    A0A9D4PG44
    Related
    XP_037525399.1, XM_037669471.2
    Conserved Domains (2) summary
    cd01446
    Location:11131
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14568
    Location:153292
    DSP_MKP_classIII; dual specificity phosphatase domain of class III mitogen-activated protein kinase phosphatase
  3. XM_037669470.2XP_037525398.1  dual specificity protein phosphatase 8 isoform X1

    UniProtKB/TrEMBL
    A0A9D4PG44
    Related
    XP_037525398.1, XM_037669470.2
    Conserved Domains (2) summary
    cd01446
    Location:11131
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14568
    Location:153292
    DSP_MKP_classIII; dual specificity phosphatase domain of class III mitogen-activated protein kinase phosphatase