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DOT1L DOT1 like histone lysine methyltransferase [ Balaenoptera musculus (blue whale) ]

Gene ID: 118893214, updated on 20-Mar-2024

Summary

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Gene symbol
DOT1L
Gene description
DOT1 like histone lysine methyltransferase
See related
EnsemblRapid:ENSBMSG00010009150
Gene type
protein coding
RefSeq status
MODEL
Organism
Balaenoptera musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
Orthologs
human mouse all
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Genomic context

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See DOT1L in Genome Data Viewer
Location:
chromosome: 3
Exon count:
29
Annotation release Status Assembly Chr Location
100 current mBalMus1.pri.v3 (GCF_009873245.2) 3 NC_045787.1 (169835529..169893817, complement)

Chromosome 3 - NC_045787.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3a subunit 2 Neighboring gene pleckstrin homology domain containing J1 Neighboring gene ornithine decarboxylase antizyme 1 Neighboring gene PEAK family member 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045787.1 Chromosome 3 Reference mBalMus1.pri.v3 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K79 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription regulatory region DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase, H3 lysine-79 specific

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Balaenoptera musculus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mBalMus1.pri.v3 Primary Assembly

Genomic

  1. NC_045787.1 Reference mBalMus1.pri.v3 Primary Assembly

    Range
    169835529..169893817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036848517.1 → XP_036704412.1  histone-lysine N-methyltransferase, H3 lysine-79 specific

    UniProtKB/TrEMBL
    A0A8B8X459, A0A8C0CZG0
    Related
    ENSBMSP00010012623.2, ENSBMST00010014036.2
    Conserved Domains (4) summary
    pfam08123
    Location:115 → 317
    DOT1; Histone methylation protein DOT1
    PHA03307
    Location:776 → 1120
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:505 → 654
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    cd20902
    Location:479 → 540
    CC_DOT1L; coiled coil domain of disruptor of telomeric-silencing 1-like (DOT1L) and similar proteins
Nucleotide Protein
Heading Accession and Version

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