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FAM24A family with sequence similarity 24 member A [ Homo sapiens (human) ]

Gene ID: 118670, updated on 2-Nov-2024

Summary

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Official Symbol
FAM24Aprovided by HGNC
Official Full Name
family with sequence similarity 24 member Aprovided by HGNC
Primary source
HGNC:HGNC:23470
See related
Ensembl:ENSG00000203795 AllianceGenome:HGNC:23470
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis (RPKM 5.4) See more
Orthologs
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Genomic context

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See FAM24A in Genome Data Viewer
Location:
10q26.13
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (122910610..122913111)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (123785583..123788099)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (124670126..124672627)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene FAM24B-CUZD1 readthrough Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:124605161-124605662 Neighboring gene CUB and zona pellucida like domains 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:124605663-124606162 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:124606229-124607110 Neighboring gene Sharpr-MPRA regulatory region 14360 Neighboring gene family with sequence similarity 24 member B Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:124635306-124635826 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:124635827-124636346 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:124644309-124644439 Neighboring gene C10orf88B (pseudogene) Neighboring gene Sharpr-MPRA regulatory region 13232 Neighboring gene chromosome 10 open reading frame 88 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2894 Neighboring gene uncharacterized LOC124902519

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy. Liu C, et al. Cancer Res, 2019 May 1. PMID 30862715, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein FAM24A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029888.3 → NP_001025059.1  protein FAM24A precursor

    See identical proteins and their annotated locations for NP_001025059.1

    Status: VALIDATED

    Source sequence(s)
    AC073585, BX109949
    Consensus CDS
    CCDS31304.1
    UniProtKB/Swiss-Prot
    A6NFZ4
    Related
    ENSP00000357889.1, ENST00000368894.2
    Conserved Domains (1) summary
    pfam15193
    Location:33 → 105
    FAM24; FAM24 family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    122910610..122913111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015639.2 → XP_016871128.1  protein FAM24A isoform X1

    UniProtKB/Swiss-Prot
    A6NFZ4
    Conserved Domains (1) summary
    pfam15193
    Location:33 → 105
    FAM24; FAM24 family

  2. XM_017015638.2 → XP_016871127.1  protein FAM24A isoform X1

    UniProtKB/Swiss-Prot
    A6NFZ4
    Conserved Domains (1) summary
    pfam15193
    Location:33 → 105
    FAM24; FAM24 family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    123785583..123788099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054364710.1 → XP_054220685.1  protein FAM24A isoform X1

    UniProtKB/Swiss-Prot
    A6NFZ4

  2. XM_054364711.1 → XP_054220686.1  protein FAM24A isoform X1

    UniProtKB/Swiss-Prot
    A6NFZ4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NFZ4.1 GenPept UniProtKB/Swiss-Prot:A6NFZ4

Gene LinkOut

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