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Aprt adenine phosphoribosyl transferase [ Mus musculus (house mouse) ]

Gene ID: 11821, updated on 25-Nov-2021

Summary

Official Symbol
Aprtprovided by MGI
Official Full Name
adenine phosphoribosyl transferaseprovided by MGI
Primary source
MGI:MGI:88061
See related
Ensembl:ENSMUSG00000006589
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C85684
Expression
Broad expression in duodenum adult (RPKM 258.1), placenta adult (RPKM 212.8) and 23 other tissues See more
Orthologs
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Genomic context

See Aprt in Genome Data Viewer
Location:
8 E1; 8 71.91 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (123301376..123303646, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (122574637..122576907, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (125098537..125100807, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34847 Neighboring gene chromatin licensing and DNA replication factor 1 Neighboring gene galactosamine (N-acetyl)-6-sulfate sulfatase Neighboring gene predicted gene, 34962 Neighboring gene 60S ribosomal protein L30 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11749

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables AMP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables AMP binding ISO
Inferred from Sequence Orthology
more info
 
enables adenine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables adenine binding IDA
Inferred from Direct Assay
more info
PubMed 
enables adenine phosphoribosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables adenine phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables adenine phosphoribosyltransferase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables adenine phosphoribosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in AMP salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in AMP salvage IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within AMP salvage IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in AMP salvage IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in GMP salvage IDA
Inferred from Direct Assay
more info
PubMed 
involved_in IMP salvage IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within adenine metabolic process IC
Inferred by Curator
more info
PubMed 
acts_upstream_of_or_within adenine metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within adenine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in adenine salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT acts_upstream_of_or_within grooming behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within grooming behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in lactation ISO
Inferred from Sequence Orthology
more info
 
involved_in nucleoside metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within purine ribonucleoside salvage IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within purine ribonucleoside salvage IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
adenine phosphoribosyltransferase
NP_033828.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009698.2NP_033828.2  adenine phosphoribosyltransferase

    See identical proteins and their annotated locations for NP_033828.2

    Status: VALIDATED

    Source sequence(s)
    AK153201, BY115322
    Consensus CDS
    CCDS40503.1
    UniProtKB/Swiss-Prot
    P08030
    Related
    ENSMUSP00000006764.8, ENSMUST00000006764.9
    Conserved Domains (1) summary
    PRK02304
    Location:6180
    PRK02304; adenine phosphoribosyltransferase; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    123301376..123303646 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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