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SNAP47 synaptosome associated protein 47 [ Homo sapiens (human) ]

Gene ID: 116841, updated on 9-Jun-2020

Summary

Official Symbol
SNAP47provided by HGNC
Official Full Name
synaptosome associated protein 47provided by HGNC
Primary source
HGNC:HGNC:30669
See related
Ensembl:ENSG00000143740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SVAP1; HEL170; SNAP-47; C1orf142; ESFI5812; HEL-S-290
Expression
Ubiquitous expression in testis (RPKM 8.2), ovary (RPKM 7.5) and 25 other tissues See more
Orthologs

Genomic context

See SNAP47 in Genome Data Viewer
Location:
1q42.13
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (227728168..227781231)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (227922697..227968932)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene zinc finger protein 678 Neighboring gene vomeronasal 1 receptor 15 pseudogene Neighboring gene zinc finger protein 847, pseudogene Neighboring gene jumonji domain containing 4 Neighboring gene LOC105373289 Neighboring gene serine protease 38

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12517, FLJ30704, FLJ36417, DKFZp686M10160

Gene Ontology Provided by GOA

Function Evidence Code Pubs
SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
exocytic insertion of neurotransmitter receptor to postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle fusion to presynaptic active zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle priming IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with BLOC-1 complex IDA
Inferred from Direct Assay
more info
PubMed 
SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
hippocampal mossy fiber to CA3 synapse IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic density IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
synaptosomal-associated protein 47
Names
epididymis luminal protein 170
epididymis secretory protein Li 290
synaptosomal-associated 47 kDa protein
synaptosomal-associated protein, 47kDa
synaptosome associated protein 47kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001323930.1NP_001310859.1  synaptosomal-associated protein 47 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Consensus CDS
    CCDS81429.1
    UniProtKB/TrEMBL
    A0A087X0B7
    Conserved Domains (3) summary
    cd15854
    Location:359417
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:106170
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:4298
    PH-like; Pleckstrin homology-like domain
  2. NM_001323931.1NP_001310860.1  synaptosomal-associated protein 47 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Consensus CDS
    CCDS81429.1
    UniProtKB/TrEMBL
    A0A087X0B7
    Conserved Domains (3) summary
    cd15854
    Location:359417
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:106170
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:4298
    PH-like; Pleckstrin homology-like domain
  3. NM_001323932.1NP_001310861.1  synaptosomal-associated protein 47 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Consensus CDS
    CCDS81429.1
    UniProtKB/TrEMBL
    A0A087X0B7
    Conserved Domains (3) summary
    cd15854
    Location:359417
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:106170
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:4298
    PH-like; Pleckstrin homology-like domain
  4. NM_001323933.1NP_001310862.1  synaptosomal-associated protein 47 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Consensus CDS
    CCDS81429.1
    UniProtKB/TrEMBL
    A0A087X0B7
    Conserved Domains (3) summary
    cd15854
    Location:359417
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:106170
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:4298
    PH-like; Pleckstrin homology-like domain
  5. NM_001323934.1NP_001310863.1  synaptosomal-associated protein 47 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Consensus CDS
    CCDS81429.1
    UniProtKB/TrEMBL
    A0A087X0B7
    Related
    ENSP00000483253.1, ENST00000617596.4
    Conserved Domains (3) summary
    cd15854
    Location:359417
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:106170
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:4298
    PH-like; Pleckstrin homology-like domain
  6. NM_001323935.1NP_001310864.1  synaptosomal-associated protein 47 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL136378
    UniProtKB/Swiss-Prot
    Q5SQN1
    Related
    ENSP00000411128.1, ENST00000426344.5
  7. NM_053052.3NP_444280.2  synaptosomal-associated protein 47 isoform a

    See identical proteins and their annotated locations for NP_444280.2

    Status: VALIDATED

    Source sequence(s)
    AY090635, BC014059, BC025231
    Consensus CDS
    CCDS1562.1
    UniProtKB/Swiss-Prot
    Q5SQN1
    Related
    ENSP00000314157.6, ENST00000315781.9
    Conserved Domains (3) summary
    cd15854
    Location:404462
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:151215
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:87143
    PH-like; Pleckstrin homology-like domain

RNA

  1. NR_136654.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
    Related
    ENST00000366760.5
  2. NR_136655.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
  3. NR_136656.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL136378, AL731702
  4. NR_136657.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL136378
    Related
    ENST00000418653.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    227728168..227781231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017000232.1XP_016855721.1  synaptosomal-associated protein 47 isoform X1

    UniProtKB/Swiss-Prot
    Q5SQN1
    Conserved Domains (3) summary
    cd15854
    Location:404462
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:151215
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:87143
    PH-like; Pleckstrin homology-like domain
  2. XM_017000231.2XP_016855720.1  synaptosomal-associated protein 47 isoform X1

    UniProtKB/Swiss-Prot
    Q5SQN1
    Conserved Domains (3) summary
    cd15854
    Location:404462
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:151215
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:87143
    PH-like; Pleckstrin homology-like domain
  3. XM_006711734.3XP_006711797.1  synaptosomal-associated protein 47 isoform X2

    Conserved Domains (3) summary
    cd15854
    Location:375433
    SNARE_SNAP47C; C-terminal SNARE motif of SNAP47
    cd15888
    Location:122186
    SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
    cl17171
    Location:58114
    PH-like; Pleckstrin homology-like domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_024485.1: Suppressed sequence

    Description
    NR_024485.1: This RefSeq was removed because currently there is insufficient support for the transcript.
  2. NR_024486.1: Suppressed sequence

    Description
    NR_024486.1: This RefSeq was removed because currently there is insufficient support for the transcript.
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