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BATF2 basic leucine zipper ATF-like transcription factor 2 [ Homo sapiens (human) ]

Gene ID: 116071, updated on 24-Dec-2019

Summary

Official Symbol
BATF2provided by HGNC
Official Full Name
basic leucine zipper ATF-like transcription factor 2provided by HGNC
Primary source
HGNC:HGNC:25163
See related
Ensembl:ENSG00000168062 MIM:614983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SARI
Expression
Broad expression in spleen (RPKM 7.0), appendix (RPKM 4.9) and 23 other tissues See more
Orthologs

Genomic context

See BATF2 in Genome Data Viewer
Location:
11q13.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (64987945..64996971, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64755417..64765060, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B'beta Neighboring gene glycoprotein hormone subunit alpha 2 Neighboring gene membrane anchored junction protein Neighboring gene CRISPRi-validated cis-regulatory element chr11.3163 Neighboring gene ARL2-SNX15 readthrough (NMD candidate) Neighboring gene microRNA 6879 Neighboring gene ADP ribosylation factor like GTPase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC20410

Gene Ontology Provided by GOA

Process Evidence Code Pubs
defense response to protozoan ISS
Inferred from Sequence or Structural Similarity
more info
 
myeloid dendritic cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
basic leucine zipper transcriptional factor ATF-like 2
Names
B-ATF-2
basic leucine zipper transcription factor, ATF-like 2
suppressor of AP-1 regulated by IFN

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300807.1NP_001287736.1  basic leucine zipper transcriptional factor ATF-like 2 isoform 2

    See identical proteins and their annotated locations for NP_001287736.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate exon in place of the first two exons compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AK300917, BP206576, HM134154
    Consensus CDS
    CCDS76429.1
    UniProtKB/Swiss-Prot
    Q8N1L9
    UniProtKB/TrEMBL
    B4DV37
    Related
    ENSP00000434915.1, ENST00000527716.1
    Conserved Domains (1) summary
    cl21462
    Location:2350
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
  2. NM_001300808.1NP_001287737.1  basic leucine zipper transcriptional factor ATF-like 2 isoform 3

    See identical proteins and their annotated locations for NP_001287737.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate exon in place of the first two exons compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK092453, BP206576, HM134154
    Consensus CDS
    CCDS73317.1
    UniProtKB/Swiss-Prot
    Q8N1L9
    Related
    ENSP00000398911.2, ENST00000435842.2
    Conserved Domains (1) summary
    PRK10263
    Location:24125
    PRK10263; DNA translocase FtsK; Provisional
  3. NM_138456.4NP_612465.3  basic leucine zipper transcriptional factor ATF-like 2 isoform 1

    See identical proteins and their annotated locations for NP_612465.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK096702, BC012330
    Consensus CDS
    CCDS8087.1
    UniProtKB/Swiss-Prot
    Q8N1L9
    Related
    ENSP00000301887.4, ENST00000301887.9
    Conserved Domains (1) summary
    cd14701
    Location:1774
    bZIP_BATF; Basic leucine zipper (bZIP) domain of BATF proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    64987945..64996971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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