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SMIM19 small integral membrane protein 19 [ Homo sapiens (human) ]

Gene ID: 114926, updated on 7-Jun-2020

Summary

Official Symbol
SMIM19provided by HGNC
Official Full Name
small integral membrane protein 19provided by HGNC
Primary source
HGNC:HGNC:25166
See related
Ensembl:ENSG00000176209
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8orf40
Expression
Ubiquitous expression in thyroid (RPKM 18.5), kidney (RPKM 14.5) and 25 other tissues See more
Orthologs

Genomic context

See SMIM19 in Genome Data Viewer
Location:
8p11.21
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (42541148..42555195)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (42396298..42408140)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene dickkopf WNT signaling pathway inhibitor 4 Neighboring gene voltage dependent anion channel 3 Neighboring gene solute carrier family 20 member 2 Neighboring gene uncharacterized LOC105379396 Neighboring gene ribosomal protein L7 like 1 pseudogene Neighboring gene cholinergic receptor nicotinic beta 3 subunit

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 19
Names
UPF0697 protein C8orf40

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135674.2NP_001129146.1  small integral membrane protein 19 isoform 1

    See identical proteins and their annotated locations for NP_001129146.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC090739, DB519016
    Consensus CDS
    CCDS6133.2
    UniProtKB/Swiss-Prot
    Q96E16
    Related
    ENSP00000405694.2, ENST00000417410.6
    Conserved Domains (1) summary
    pfam15117
    Location:10107
    UPF0697; Uncharacterized protein family UPF0697
  2. NM_001135675.2NP_001129147.1  small integral membrane protein 19 isoform 1

    See identical proteins and their annotated locations for NP_001129147.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC090739, AK311932, BC013035, BI335341, BI549696, DB519016
    Consensus CDS
    CCDS6133.2
    UniProtKB/Swiss-Prot
    Q96E16
    Related
    ENSP00000390750.2, ENST00000416469.6
    Conserved Domains (1) summary
    pfam15117
    Location:10107
    UPF0697; Uncharacterized protein family UPF0697
  3. NM_001135676.2NP_001129148.1  small integral membrane protein 19 isoform 1

    See identical proteins and their annotated locations for NP_001129148.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC090739, BI463786, DB519016
    Consensus CDS
    CCDS6133.2
    UniProtKB/Swiss-Prot
    Q96E16
    Related
    ENSP00000391549.2, ENST00000438528.7
    Conserved Domains (1) summary
    pfam15117
    Location:10107
    UPF0697; Uncharacterized protein family UPF0697
  4. NM_001363186.2NP_001350115.1  small integral membrane protein 19 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC090739, BX389412, HY008367
    Conserved Domains (1) summary
    pfam15117
    Location:17114
    UPF0697; Uncharacterized protein family UPF0697
  5. NM_138436.4NP_612445.2  small integral membrane protein 19 isoform 1

    See identical proteins and their annotated locations for NP_612445.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC090739, BC013035, DA702519, DB519016
    Consensus CDS
    CCDS6133.2
    UniProtKB/Swiss-Prot
    Q96E16
    Related
    ENSP00000408997.2, ENST00000414154.6
    Conserved Domains (1) summary
    pfam15117
    Location:10107
    UPF0697; Uncharacterized protein family UPF0697

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    42541148..42555195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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