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ARHGAP44 Rho GTPase activating protein 44 [ Podarcis muralis (Common wall lizard) ]

Gene ID: 114590737, updated on 15-Mar-2024

Summary

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Gene symbol
ARHGAP44
Gene description
Rho GTPase activating protein 44
See related
Ensembl:ENSPMRG00000015520
Gene type
protein coding
RefSeq status
MODEL
Organism
Podarcis muralis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Podarcis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
23
Annotation release Status Assembly Chr Location
100 current PodMur_1.0 (GCF_004329235.1) 2 NC_041313.1 (39411839..39502165)

Chromosome 2 - NC_041313.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2C20-like Neighboring gene cytochrome P450 2C8-like Neighboring gene uncharacterized LOC114590736 Neighboring gene cytochrome P450 2G1-like Neighboring gene testis-expressed protein 47-like Neighboring gene ubiquitin specific peptidase 43

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041313.1 Chromosome 2 Reference PodMur_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in modification of dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Rac protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in leading edge membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Podarcis muralis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PodMur_1.0 Primary Assembly

Genomic

  1. NC_041313.1 Reference PodMur_1.0 Primary Assembly

    Range
    39411839..39502165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028717154.1 → XP_028572987.1  rho GTPase-activating protein 44 isoform X4

    UniProtKB/TrEMBL
    A0A670JHV1
    Related
    ENSPMRP00000024031.1, ENSPMRT00000025495.1
    Conserved Domains (3) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:552 → 645
    dnaA; chromosomal replication initiation protein; Provisional
    cd04386
    Location:249 → 449
    RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

  2. XM_028717151.1 → XP_028572984.1  rho GTPase-activating protein 44 isoform X1

    UniProtKB/TrEMBL
    A0A670JHV1
    Conserved Domains (3) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:552 → 645
    dnaA; chromosomal replication initiation protein; Provisional
    cd04386
    Location:249 → 449
    RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

  3. XM_028717157.1 → XP_028572990.1  rho GTPase-activating protein 44 isoform X6

    Conserved Domains (3) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:552 → 645
    dnaA; chromosomal replication initiation protein; Provisional
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_028717158.1 → XP_028572991.1  rho GTPase-activating protein 44 isoform X7

    Conserved Domains (3) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:552 → 645
    dnaA; chromosomal replication initiation protein; Provisional
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_028717152.1 → XP_028572985.1  rho GTPase-activating protein 44 isoform X2

    UniProtKB/TrEMBL
    A0A670JHV1
    Conserved Domains (3) summary
    cd07619
    Location:13 → 259
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:551 → 644
    dnaA; chromosomal replication initiation protein; Provisional
    cd04386
    Location:248 → 448
    RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

  6. XM_028717153.1 → XP_028572986.1  rho GTPase-activating protein 44 isoform X3

    UniProtKB/TrEMBL
    A0A670JHV1
    Conserved Domains (3) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    PRK14086
    Location:546 → 639
    dnaA; chromosomal replication initiation protein; Provisional
    cd04386
    Location:249 → 449
    RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

  7. XM_028717155.1 → XP_028572988.1  rho GTPase-activating protein 44 isoform X5

    Conserved Domains (2) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  8. XM_028717159.1 → XP_028572992.1  rho GTPase-activating protein 44 isoform X8

    Conserved Domains (2) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  9. XM_028717160.1 → XP_028572993.1  rho GTPase-activating protein 44 isoform X9

    Conserved Domains (2) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_028717161.1 → XP_028572994.1  rho GTPase-activating protein 44 isoform X10

    Conserved Domains (2) summary
    cd07619
    Location:13 → 260
    BAR_Rich2; The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2
    cl02570
    Location:249 → 449
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
Nucleotide Protein
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