U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 [ Mus musculus (house mouse) ]

Gene ID: 11416, updated on 5-Mar-2024

Summary

Official Symbol
Slc33a1provided by MGI
Official Full Name
solute carrier family 33 (acetyl-CoA transporter), member 1provided by MGI
Primary source
MGI:MGI:1332247
See related
Ensembl:ENSMUSG00000027822 AllianceGenome:MGI:1332247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Acatn; D630022N01Rik
Summary
Predicted to enable solute:proton symporter activity. Predicted to be involved in BMP signaling pathway and SMAD protein signal transduction. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; heart; liver; metanephros; and spleen. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Orthologous to human SLC33A1 (solute carrier family 33 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 15.9), adrenal adult (RPKM 12.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Slc33a1 in Genome Data Viewer
Location:
3 E1; 3 30.08 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (63849744..63872154, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (63942323..63964733, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA E130311K13 gene Neighboring gene predicted gene, 34379 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:63768480-63768744 Neighboring gene STARR-positive B cell enhancer ABC_E2666 Neighboring gene STARR-seq mESC enhancer starr_07841 Neighboring gene guanine monophosphate synthetase Neighboring gene vomeronasal 2, receptor, pseudogene 3 Neighboring gene vomeronasal 2, receptor 1 Neighboring gene predicted gene, 22165

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetyl-CoA transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in acetyl-CoA transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
acetyl-coenzyme A transporter 1
Names
AT-1
acetyl-CoA transporter 1
solute carrier family 33 member 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001272035.1NP_001258964.1  acetyl-coenzyme A transporter 1 isoform 1

    See identical proteins and their annotated locations for NP_001258964.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC116732, AW519598
    Consensus CDS
    CCDS17382.1
    UniProtKB/Swiss-Prot
    Q99J27, Q9WTN1
    Related
    ENSMUSP00000125713.2, ENSMUST00000160883.2
    Conserved Domains (1) summary
    TIGR00901
    Location:86459
    2A0125; AmpG-like permease
  2. NM_001331067.1NP_001317996.1  acetyl-coenzyme A transporter 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses an alternate translation start site compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC116732
  3. NM_015728.5NP_056543.2  acetyl-coenzyme A transporter 1 isoform 1

    See identical proteins and their annotated locations for NP_056543.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC116732, AW519598
    Consensus CDS
    CCDS17382.1
    UniProtKB/Swiss-Prot
    Q99J27, Q9WTN1
    Related
    ENSMUSP00000029402.9, ENSMUST00000029402.15
    Conserved Domains (1) summary
    TIGR00901
    Location:86459
    2A0125; AmpG-like permease

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    63849744..63872154 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)