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MTMR4 myotubularin related protein 4 [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111163628, updated on 15-Mar-2024

Summary

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Gene symbol
MTMR4
Gene description
myotubularin related protein 4
See related
Ensembl:ENSDLEG00000006847
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098032.1 (5881633..5905620, complement)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160928.1 (5850177..5874269, complement)

NW_022098032.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 43 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene heat shock transcription factor 5 Neighboring gene septin 4 Neighboring gene testis expressed 14, intercellular bridge forming factor Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myotubularin-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098032.1 Reference ASM228892v3 Primary Assembly

    Range
    5881633..5905620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022552484.2 → XP_022408192.1  myotubularin-related protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9LS89
    Related
    ENSDLEP00000009373.1, ENSDLET00000010340.1
    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1112 → 1171
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  2. XM_022552485.2 → XP_022408193.1  myotubularin-related protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9LS89
    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1112 → 1171
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  3. XM_030763144.1 → XP_030619004.1  myotubularin-related protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9LS89
    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1112 → 1171
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  4. XM_022552482.1 → XP_022408190.1  myotubularin-related protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9LF34
    Related
    ENSDLEP00000009381.1, ENSDLET00000010351.1
    Conserved Domains (3) summary
    cd13342
    Location:37 → 150
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1126 → 1185
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    pfam06602
    Location:174 → 533
    Myotub-related; Myotubularin-like phosphatase domain

  5. XM_022552481.1 → XP_022408189.1  myotubularin-related protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9LEU0
    Conserved Domains (3) summary
    cd13342
    Location:38 → 151
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1127 → 1186
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    pfam06602
    Location:175 → 534
    Myotub-related; Myotubularin-like phosphatase domain
Nucleotide Protein
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