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ITPR2 inositol 1,4,5-trisphosphate receptor type 2 [ Enhydra lutris kenyoni (northern sea otter) ]

Gene ID: 111159979, updated on 5-Aug-2024

Summary

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Gene symbol
ITPR2
Gene description
inositol 1,4,5-trisphosphate receptor type 2
See related
EnsemblRapid:ENSELKG00000021326
Gene type
protein coding
RefSeq status
MODEL
Organism
Enhydra lutris kenyoni (sub-species: kenyoni)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Lutrinae; Enhydra
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
59
Annotation release Status Assembly Chr Location
100 current ASM228890v2 (GCF_002288905.1) Unplaced Scaffold NW_019154156.1 (3917182..4407191, complement)

NW_019154156.1Genomic Context describing neighboring genes Neighboring gene sarcospan Neighboring gene uncharacterized LOC111159988 Neighboring gene 60S ribosomal protein L26 pseudogene Neighboring gene integrator complex subunit 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_019154156 Unplaced Scaffold Reference ASM228890v2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol 1,4,5 trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol 1,4,5-trisphosphate receptor type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Enhydra lutris kenyoni Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228890v2 Primary Assembly

Genomic

  1. NW_019154156.1 Reference ASM228890v2 Primary Assembly

    Range
    3917182..4407191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022522705.1 → XP_022378413.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9KZA0
    Related
    ENSELKP00000028615.1, ENSELKT00000031689.1
    Conserved Domains (5) summary
    pfam00520
    Location:2290 → 2552
    Ion_trans; Ion transport protein
    pfam01365
    Location:473 → 670
    RYDR_ITPR; RIH domain
    pfam02815
    Location:232 → 432
    MIR; MIR domain
    pfam08454
    Location:1917 → 2022
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:4 → 225
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  2. XM_022522706.1 → XP_022378414.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9L462
    Conserved Domains (5) summary
    pfam00520
    Location:2228 → 2490
    Ion_trans; Ion transport protein
    pfam01365
    Location:411 → 608
    RYDR_ITPR; RIH domain
    pfam02815
    Location:170 → 370
    MIR; MIR domain
    pfam08454
    Location:1855 → 1960
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:1 → 163
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  3. XM_022522707.1 → XP_022378415.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9LAB9
    Related
    ENSELKP00000028794.1, ENSELKT00000031884.1
    Conserved Domains (5) summary
    pfam00520
    Location:2290 → 2552
    Ion_trans; Ion transport protein
    pfam01365
    Location:473 → 670
    RYDR_ITPR; RIH domain
    pfam02815
    Location:232 → 432
    MIR; MIR domain
    pfam08454
    Location:1917 → 2022
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:4 → 225
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
Nucleotide Protein
Heading Accession and Version

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