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TMPRSS2 transmembrane serine protease 2 [ Enhydra lutris kenyoni (northern sea otter) ]

Gene ID: 111155673, updated on 15-Mar-2024

Summary

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Gene symbol
TMPRSS2
Gene description
transmembrane serine protease 2
See related
EnsemblRapid:ENSELKG00000006734
Gene type
protein coding
RefSeq status
MODEL
Organism
Enhydra lutris kenyoni (sub-species: kenyoni)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Lutrinae; Enhydra
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
100 current ASM228890v2 (GCF_002288905.1) Unplaced Scaffold NW_019154127.1 (11778742..11807946, complement)

NW_019154127.1Genomic Context describing neighboring genes Neighboring gene MX dynamin like GTPase 2 Neighboring gene MX dynamin like GTPase 1 Neighboring gene keratin-associated protein 10-3-like Neighboring gene keratin-associated protein 12-1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_019154127 Unplaced Scaffold Reference ASM228890v2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein autoprocessing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Enhydra lutris kenyoni Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228890v2 Primary Assembly

Genomic

  1. NW_019154127.1 Reference ASM228890v2 Primary Assembly

    Range
    11778742..11807946 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022515963.1 → XP_022371671.1  transmembrane protease serine 2

    UniProtKB/TrEMBL
    A0A2Y9KDU8
    Related
    ENSELKP00000008758.1, ENSELKT00000009843.1
    Conserved Domains (3) summary
    cd00112
    Location:113 → 148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:256 → 487
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153 → 246
    SRCR_2; Scavenger receptor cysteine-rich domain
Nucleotide Protein
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