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DEPP1 DEPP1 autophagy regulator [ Homo sapiens (human) ]

Gene ID: 11067, updated on 1-Jun-2020

Summary

Official Symbol
DEPP1provided by HGNC
Official Full Name
DEPP1 autophagy regulatorprovided by HGNC
Primary source
HGNC:HGNC:23355
See related
Ensembl:ENSG00000165507 MIM:611309
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FIG; DEPP; Fseg; C10orf10
Summary
The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]
Expression
Broad expression in fat (RPKM 86.3), endometrium (RPKM 51.4) and 24 other tissues See more
Orthologs

Genomic context

See DEPP1 in Genome Data Viewer
Location:
10q11.21
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (44976128..44978809, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (45471709..45474330, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 4 Neighboring gene Sharpr-MPRA regulatory region 2327 Neighboring gene uncharacterized LOC105378281 Neighboring gene Sharpr-MPRA regulatory region 8316 Neighboring gene ZNF22 antisense RNA 1 Neighboring gene zinc finger protein 22

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
autophagy IEA
Inferred from Electronic Annotation
more info
 
regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of autophagy IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein DEPP1
Names
decidual protein induced by progesterone
fasting induced
fasting-induced gene protein
fasting-induced protein
fat-specific expressed
protein DEPP

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007021.4NP_008952.1  protein DEPP1

    See identical proteins and their annotated locations for NP_008952.1

    Status: REVIEWED

    Source sequence(s)
    AL353801, DB030770
    Consensus CDS
    CCDS7210.1
    UniProtKB/Swiss-Prot
    Q9NTK1
    Related
    ENSP00000298295.3, ENST00000298295.4
    Conserved Domains (1) summary
    pfam15343
    Location:25212
    DEPP; Decidual protein induced by progesterone family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    44976128..44978809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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