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SCO6266 ScbA protein [ Streptomyces coelicolor A3(2) ]

Gene ID: 1101707, discontinued on 9-Sep-2022
  • This record was discontinued.

Summary

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Gene symbol
SCO6266
Gene description
ScbA protein
Locus tag
SCO6266
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
SCAH10.31; scbA
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ScbR2 negatively controls the biosynthesis of gamma-butyrolactone by directly repressing the transcription of scbA.
    Title: A novel role of 'pseudo'γ-butyrolactone receptors in controlling γ-butyrolactone biosynthesis in Streptomyces.
  2. The gamma-butyrolactone synthase ScbA is responsible for the biosynthesis of signalling molecules.
    Title: Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2).
  3. The two predicted active sites in ScbA were mutated and gamma-butyrolactone biosynthesis was abolished suggesting that ScbA has enzymic activity.
    Title: ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize gamma-butyrolactones.
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General gene information

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Homology

General protein information

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Names
ScbA protein
NP_630366.1
  • SCAH10.31, scbA, len: 314 aa; identical to previously sequenced TR:O86851 (EMBL:AJ007731) Streptomyces coelicolor ScbA protein, 314 aa and to SW:AFSA_STRGR (EMBL:M24250) Streptomyces griseus possible A-factor biosynthesis enzyme AfsA, 301 aa; fasta scores: opt: 1345 z-score: 1570.4 E(): 0; 66.1% identity in 292 aa overlap

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    6891293..6892237
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_630366.1 ScbA protein [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
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Gene LinkOut

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Molecular Biology Databases