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RIGI RNA sensor RIG-I [ Panthera pardus (leopard) ]

Gene ID: 109252056, updated on 14-Mar-2024

Summary

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Gene symbol
RIGI
Gene description
RNA sensor RIG-I
See related
Ensembl:ENSPPRG00000010161
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera pardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Also known as
DDX58
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_02 current ASM2436296v1 (GCF_024362965.1) Unplaced Scaffold NW_026526766.1 (54585390..54626152, complement)
100 previous assembly PanPar1.0 (GCF_001857705.1) Unplaced Scaffold NW_017619942.1 (1797470..1840397)

NW_026526766.1Genomic Context describing neighboring genes Neighboring gene GTP-binding nuclear protein Ran-like Neighboring gene aconitase 1 Neighboring gene TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase Neighboring gene small integral membrane protein 27 Neighboring gene NADH:ubiquinone oxidoreductase subunit B6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
antiviral innate immune response receptor RIG-I
Names
DExD/H-box helicase 58

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024362965.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2436296v1 Primary Assembly

Genomic

  1. NW_026526766.1 Reference ASM2436296v1 Primary Assembly

    Range
    54585390..54626152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019424183.2 → XP_019279728.1  antiviral innate immune response receptor RIG-I isoform X4

    UniProtKB/TrEMBL
    A0A9V1EEH2

  2. XM_019424182.2 → XP_019279727.1  antiviral innate immune response receptor RIG-I isoform X3

    UniProtKB/TrEMBL
    A0A9V1EE91
    Conserved Domains (5) summary
    COG1111
    Location:199 → 760
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd08817
    Location:100 → 188
    CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat
    cd15805
    Location:768 → 881
    RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor
    cd18073
    Location:199 → 400
    DEXHc_RIG-I_DDX58; DEXH-box helicase domain of RIG-I
    cl14633
    Location:2 → 92
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_053908037.1 → XP_053764012.1  antiviral innate immune response receptor RIG-I isoform X2

    UniProtKB/TrEMBL
    A0A9W2VZH2

  4. XM_019424181.2 → XP_019279726.1  antiviral innate immune response receptor RIG-I isoform X1

    UniProtKB/TrEMBL
    A0A9V1EE70
    Related
    ENSPPRP00000018517.1
    Conserved Domains (5) summary
    COG1111
    Location:240 → 801
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd08817
    Location:100 → 188
    CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat
    cd15805
    Location:809 → 922
    RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor
    cd18073
    Location:240 → 441
    DEXHc_RIG-I_DDX58; DEXH-box helicase domain of RIG-I
    cl14633
    Location:2 → 92
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein
Heading Accession and Version

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