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fxr1 FMR1 autosomal homolog 1 [ Cyprinodon variegatus (sheepshead minnow) ]

Gene ID: 107095766, updated on 14-Mar-2024

Summary

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Gene symbol
fxr1
Gene description
FMR1 autosomal homolog 1
See related
Ensembl:ENSCVAG00000000711
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyprinodon variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae; Cyprinodon
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current C_variegatus-1.0 (GCF_000732505.1) Unplaced Scaffold NW_015151024.1 (401909..416610, complement)

NW_015151024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107095762 Neighboring gene SRY-box transcription factor 2 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 19 Neighboring gene tetratricopeptide repeat domain 14 Neighboring gene uncharacterized LOC107095764

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015151024.1 Unplaced Scaffold Reference C_variegatus-1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterograde axonal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mRNA stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of modification of synaptic structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fragile X mental retardation syndrome-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyprinodon variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C_variegatus-1.0 Primary Assembly

Genomic

  1. NW_015151024.1 Reference C_variegatus-1.0 Primary Assembly

    Range
    401909..416610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015392041.1 → XP_015247527.1  fragile X mental retardation syndrome-related protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 352
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:354 → 475
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:509 → 574
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:619 → 689
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  2. XM_015392044.1 → XP_015247530.1  fragile X mental retardation syndrome-related protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Related
    ENSCVAP00000001676.1, ENSCVAT00000013020.1
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 352
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:354 → 476
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:510 → 576
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:594 → 664
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  3. XM_015392040.1 → XP_015247526.1  fragile X mental retardation syndrome-related protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 352
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:354 → 476
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:510 → 575
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:620 → 690
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  4. XM_015392039.1 → XP_015247525.1  fragile X mental retardation syndrome-related protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 354
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:356 → 477
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:511 → 576
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:621 → 691
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  5. XM_015392036.1 → XP_015247522.1  fragile X mental retardation syndrome-related protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2CAC4, A0A3Q2CAD6
    Related
    ENSCVAP00000001682.1, ENSCVAT00000013004.1
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 354
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:356 → 478
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:512 → 577
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:622 → 692
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  6. XM_015392038.1 → XP_015247524.1  fragile X mental retardation syndrome-related protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 355
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:357 → 478
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:512 → 577
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:622 → 692
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  7. XM_015392043.1 → XP_015247529.1  fragile X mental retardation syndrome-related protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 355
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:357 → 479
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:513 → 579
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:597 → 666
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  8. XM_015392042.1 → XP_015247528.1  fragile X mental retardation syndrome-related protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Related
    ENSCVAP00000001692.1, ENSCVAT00000012991.1
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 355
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:357 → 479
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:513 → 579
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:597 → 667
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  9. XM_015392037.1 → XP_015247523.1  fragile X mental retardation syndrome-related protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 355
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:357 → 479
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:513 → 578
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:623 → 692
    FXR_C3; Fragile X-related 1 protein C-terminal region 3

  10. XM_015392035.1 → XP_015247521.1  fragile X mental retardation syndrome-related protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2CAD6
    Conserved Domains (6) summary
    smart00322
    Location:217 → 280
    KH; K homology RNA-binding domain
    cd00105
    Location:286 → 355
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:70 → 118
    Agenet; Agenet domain
    pfam12235
    Location:357 → 479
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:513 → 578
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:623 → 693
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
Nucleotide Protein
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