Format

Send to:

Choose Destination

PNMA2 PNMA family member 2 [ Homo sapiens (human) ]

Gene ID: 10687, updated on 5-Apr-2020

Summary

Official Symbol
PNMA2provided by HGNC
Official Full Name
PNMA family member 2provided by HGNC
Primary source
HGNC:HGNC:9159
See related
Ensembl:ENSG00000240694 MIM:603970
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MA2; MM2; RGAG2
Expression
Biased expression in brain (RPKM 63.2), adrenal (RPKM 6.1) and 1 other tissue See more
Orthologs

Genomic context

See PNMA2 in Genome Data Viewer
Location:
8p21.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (26504695..26513872, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (26362196..26371608, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379337 Neighboring gene DNAJB6 pseudogene 2 Neighboring gene dihydropyrimidinase like 2 Neighboring gene proteasome activator subunit 2 pseudogene 5 Neighboring gene adrenoceptor alpha 1A Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0883

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
paraneoplastic antigen Ma2
Names
40 kDa neuronal protein
onconeuronal antigen MA2
paraneoplastic Ma antigen 2
paraneoplastic neuronal antigen MM2
retrotransposon gag domain containing 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007257.6NP_009188.1  paraneoplastic antigen Ma2

    See identical proteins and their annotated locations for NP_009188.1

    Status: VALIDATED

    Source sequence(s)
    AB020690, BC036489, BC047515, DA779744
    Consensus CDS
    CCDS34868.1
    UniProtKB/Swiss-Prot
    Q9UL42
    UniProtKB/TrEMBL
    Q5U5Z3
    Related
    ENSP00000429344.1, ENST00000522362.7
    Conserved Domains (1) summary
    pfam14893
    Location:1327
    PNMA; PNMA

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    26504695..26513872 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544365.3XP_011542667.1  paraneoplastic antigen Ma2 isoform X1

    See identical proteins and their annotated locations for XP_011542667.1

    UniProtKB/Swiss-Prot
    Q9UL42
    Conserved Domains (1) summary
    pfam14893
    Location:1327
    PNMA; PNMA
Support Center