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tet2 tet methylcytosine dioxygenase 2 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105939860, updated on 13-Mar-2024

Summary

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Gene symbol
tet2
Gene description
tet methylcytosine dioxygenase 2
See related
Ensembl:ENSFHEG00000021818
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Orthologs
human zebrafish all
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Genomic context

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See tet2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 5 NC_046365.1 (17686702..17721100)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234560.1 (218383..263569, complement)

Chromosome 5 - NC_046365.1Genomic Context describing neighboring genes Neighboring gene CXXC finger 4 Neighboring gene polyunsaturated fatty acid lipoxygenase ALOX15B-like Neighboring gene inorganic pyrophosphatase 2 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 38

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-methylcytosine dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 5-methylcytosine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in myeloid cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oxidative demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methylcytosine dioxygenase TET2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046365.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    17686702..17721100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012882188.3 → XP_012737642.2  methylcytosine dioxygenase TET2

    UniProtKB/TrEMBL
    A0A3Q2R3G8
    Conserved Domains (3) summary
    PHA03247
    Location:1309 → 1534
    PHA03247; large tegument protein UL36; Provisional
    pfam09606
    Location:251 → 631
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl40427
    Location:930 → 1267
    Tet_JBP; oxygenase domain of ten-eleven translocation (TET) enzymes, J-binding proteins (JBPs), and similar proteins
Nucleotide Protein
Heading Accession and Version

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