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Utp15 UTP15 small subunit processome component [ Mus musculus (house mouse) ]

Gene ID: 105372, updated on 26-Sep-2022

Summary

Official Symbol
Utp15provided by MGI
Official Full Name
UTP15 small subunit processome componentprovided by MGI
Primary source
MGI:MGI:2145443
See related
Ensembl:ENSMUSG00000041747 AllianceGenome:MGI:2145443
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in positive regulation of rRNA processing; positive regulation of transcription by RNA polymerase I; and rRNA processing. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in endoplasmic reticulum and fibrillar center. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.4), placenta adult (RPKM 5.9) and 28 other tissues See more
Orthologs
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Genomic context

See Utp15 in Genome Data Viewer
Location:
13; 13 D1
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (98383353..98399500, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (98246845..98262992, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor (GEF) 28 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene predicted gene, 34469 Neighboring gene ankyrin repeat, family A (RFXANK-like), 2 Neighboring gene predicted gene 21976

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in positive regulation of rRNA processing ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase I ISO
Inferred from Sequence Orthology
more info
 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
U3 small nucleolar RNA-associated protein 15 homolog
Names
UTP15, U3 small nucleolar ribonucleoprotein, homolog
src-associated protein SAW

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178918.3NP_849249.1  U3 small nucleolar RNA-associated protein 15 homolog

    See identical proteins and their annotated locations for NP_849249.1

    Status: PROVISIONAL

    Source sequence(s)
    AC123056
    Consensus CDS
    CCDS26712.1
    UniProtKB/Swiss-Prot
    Q8C7V3, Q8K231
    Related
    ENSMUSP00000048204.3, ENSMUST00000040972.4
    Conserved Domains (4) summary
    COG2319
    Location:28310
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:39298
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam09384
    Location:343487
    UTP15_C; UTP15 C terminal
    sd00039
    Location:4178
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    98383353..98399500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)