U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MET MET proto-oncogene, receptor tyrosine kinase [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105085321, updated on 19-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
MET
Gene description
MET proto-oncogene, receptor tyrosine kinase
Locus tag
Cadr_000008230
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Also known as
C-met
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MET in Genome Data Viewer
Location:
chromosome: 7
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 7 NC_087442.1 (29533884..29640166, complement)
101 previous assembly CamDro3 (GCF_000803125.2) 7 NC_044517.1 (55954143..56155031)

Chromosome 7 - NC_087442.1Genomic Context describing neighboring genes Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene capping actin protein of muscle Z-line subunit alpha 2 Neighboring gene RAB11-binding protein RELCH-like Neighboring gene caveolin 1 Neighboring gene caveolin 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of semaphorin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
hepatocyte growth factor receptor
Names
F-actin-capping protein subunit alpha-2
Hepatocyte growth factor receptor
capping actin protein of muscle Z-line alpha subunit 2
capping actin protein of muscle Z-line subunit alpha 2
hepatic growth factor receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087442.1 Reference mCamDro1.pat

    Range
    29533884..29640166 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031455257.2 → XP_031311117.1  hepatocyte growth factor receptor

    Conserved Domains (7) summary
    smart00423
    Location:520 → 562
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:840 → 933
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01180
    Location:564 → 657
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:743 → 838
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd05058
    Location:1082 → 1343
    PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron
    cl15674
    Location:658 → 741
    IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
    cl15693
    Location:25 → 517
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.