Format

Send to:

Choose Destination

LRRC41 leucine rich repeat containing 41 [ Homo sapiens (human) ]

Gene ID: 10489, updated on 7-Jun-2020

Summary

Official Symbol
LRRC41provided by HGNC
Official Full Name
leucine rich repeat containing 41provided by HGNC
Primary source
HGNC:HGNC:16917
See related
Ensembl:ENSG00000132128 MIM:618753
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MUF1; PP7759
Expression
Ubiquitous expression in thyroid (RPKM 20.0), ovary (RPKM 19.8) and 25 other tissues See more
Orthologs

Genomic context

See LRRC41 in Genome Data Viewer
Location:
1p34.1-p33
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (46278400..46303366, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (46744072..46769038, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene P3R3URF-PIK3R3 readthrough Neighboring gene PIK3R3 upstream reading frame Neighboring gene tetraspanin 1 Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Neighboring gene leucine rich adaptor protein 1 Neighboring gene RAD54 like Neighboring gene ubiquinol-cytochrome c reductase hinge protein Neighboring gene NOP2/Sun RNA methyltransferase 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC126571, MGC126573

Gene Ontology Provided by GOA

Process Evidence Code Pubs
post-translational protein modification TAS
Traceable Author Statement
more info
 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
membrane HDA PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
leucine-rich repeat-containing protein 41
Names
MUF1 protein (MUF1)
elongin BC-interacting leucine-rich repeat protein
protein Muf1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006369.4NP_006360.3  leucine-rich repeat-containing protein 41

    See identical proteins and their annotated locations for NP_006360.3

    Status: VALIDATED

    Source sequence(s)
    AF370430, AK125827, BX537366, CF125098
    Consensus CDS
    CCDS533.1
    UniProtKB/Swiss-Prot
    Q15345
    Related
    ENSP00000343298.6, ENST00000343304.10
    Conserved Domains (1) summary
    cl26161
    Location:603749
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    46278400..46303366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002957992.1 RNA Sequence

  2. XR_002957994.1 RNA Sequence

Support Center