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SNHG14 small nucleolar RNA host gene 14 [ Homo sapiens (human) ]

Gene ID: 104472715, updated on 24-Nov-2020

Summary

Official Symbol
SNHG14provided by HGNC
Official Full Name
small nucleolar RNA host gene 14provided by HGNC
Primary source
HGNC:HGNC:37462
See related
MIM:616259
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
115HG; LNCAT; UBE3A-AS; UBE3AATS; UBE3A-AS1; UBE3A-ATS; NCRNA00214; U-UBE3A-ATS; IC-SNURF-SNRPN
Summary
This gene is located within the Prader-Willi critical region and produces a long, spliced paternally-imprinted RNA that initiates within a common upstream promoter region shared by the SNRPN (small nuclear ribonucleoprotein polypeptide N) and SNURF genes. This transcript serves as a host RNA for the small nucleolar RNA, C/D box 115 and 116 clusters. This RNA extends in antisense into the region of the ubiquitin protein ligase E3A gene (UBE3A), and is thought to regulate imprinted expression of UBE3A in the brain. This transcript undergoes extensive alternative splicing, and may initiate and terminate at multiple locations within this genomic region. The full-length structure of all splice forms is not determined. [provided by RefSeq, Mar 2017]
Orthologs

Genomic context

See SNHG14 in Genome Data Viewer
Location:
15q11.2
Exon count:
148
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (24823608..25419462)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 9168 Neighboring gene nuclear pore associated protein 1 Neighboring gene Sharpr-MPRA regulatory region 849 Neighboring gene small nuclear ribonucleoprotein polypeptide N Neighboring gene ribosomal protein S27 pseudogene 2 Neighboring gene ribosomal protein L5 pseudogene 1 Neighboring gene small nucleolar RNA, C/D box 107 Neighboring gene small nucleolar RNA, C/D box 108 Neighboring gene small nucleolar RNA, C/D box 64 Neighboring gene SNRPN upstream reading frame Neighboring gene Prader Willi/Angelman region RNA, SNRPN neighbor Neighboring gene small nucleolar RNA, C/D box 116-1 Neighboring gene small nucleolar RNA, C/D box 116-2 Neighboring gene small nucleolar RNA, C/D box 116-10 Neighboring gene small nucleolar RNA, C/D box 116-3 Neighboring gene small nucleolar RNA, C/D box 116-12 Neighboring gene small nucleolar RNA, C/D box 116-11 Neighboring gene small nucleolar RNA, C/D box 116-4 Neighboring gene small nucleolar RNA, C/D box 109A Neighboring gene small nucleolar RNA, C/D box 116-5 Neighboring gene small nucleolar RNA, C/D box 116-6 Neighboring gene small nucleolar RNA, C/D box 116-15 Neighboring gene small nucleolar RNA, C/D box 116-14 Neighboring gene small nucleolar RNA, C/D box 116-13 Neighboring gene Prader Willi/Angelman region RNA 5 Neighboring gene small nucleolar RNA, C/D box 116-17 Neighboring gene small nucleolar RNA, C/D box 116-16 Neighboring gene small nucleolar RNA, C/D box 116 cluster Neighboring gene small nucleolar RNA, C/D box 116-7 Neighboring gene small nucleolar RNA, C/D box 116-8 Neighboring gene small nucleolar RNA, C/D box 116-18 Neighboring gene small nucleolar RNA, C/D box 116-19 Neighboring gene small nucleolar RNA, C/D box 116-20 Neighboring gene small nucleolar RNA, C/D box 116-21 Neighboring gene small nucleolar RNA, C/D box 116-22 Neighboring gene small nucleolar RNA, C/D box 116-9 Neighboring gene small nucleolar RNA, C/D box 116-23 Neighboring gene small nucleolar RNA, C/D box 116-24 Neighboring gene small nucleolar RNA, C/D box 116-25 Neighboring gene small nucleolar RNA, C/D box 116-26 Neighboring gene small nucleolar RNA, C/D box 116-27 Neighboring gene small nucleolar RNA, C/D box 116-28 Neighboring gene small nucleolar RNA, C/D box 116-29 Neighboring gene small nucleolar RNA, C/D box 116-30 Neighboring gene Prader Willi/Angelman region RNA 6 Neighboring gene small nucleolar RNA, C/D box 115-1 Neighboring gene small nucleolar RNA, C/D box 115-10 Neighboring gene small nucleolar RNA, C/D box 115-11 Neighboring gene small nucleolar RNA, C/D box 115-2 Neighboring gene small nucleolar RNA, C/D box 115-13 Neighboring gene small nucleolar RNA, C/D box 115-12 Neighboring gene small nucleolar RNA, C/D box 115-4 Neighboring gene small nucleolar RNA, C/D box 115-3 Neighboring gene small nucleolar RNA, C/D box 115-6 Neighboring gene small nucleolar RNA, C/D box 115-14 Neighboring gene small nucleolar RNA, C/D box 115-5 Neighboring gene small nucleolar RNA, C/D box 115-16 Neighboring gene small nucleolar RNA, C/D box 115-15 Neighboring gene small nucleolar RNA, C/D box 115-8 Neighboring gene small nucleolar RNA, C/D box 115-7 Neighboring gene small nucleolar RNA, C/D box 115-9 Neighboring gene small nucleolar RNA, C/D box 115-17 Neighboring gene small nucleolar RNA, C/D box 115-18 Neighboring gene small nucleolar RNA, C/D box 115-19 Neighboring gene small nucleolar RNA, C/D box 115-20 Neighboring gene small nucleolar RNA, C/D box 115-21 Neighboring gene small nucleolar RNA, C/D box 115-22 Neighboring gene small nucleolar RNA, C/D box 115-23 Neighboring gene small nucleolar RNA, C/D box 115-24 Neighboring gene small nucleolar RNA, C/D box 115-25 Neighboring gene small nucleolar RNA, C/D box 115-27 Neighboring gene small nucleolar RNA, C/D box 115-26 Neighboring gene small nucleolar RNA, C/D box 115-28 Neighboring gene small nucleolar RNA, C/D box 115-29 Neighboring gene small nucleolar RNA, C/D box 115-30 Neighboring gene small nucleolar RNA, C/D box 115-31 Neighboring gene small nucleolar RNA, C/D box 115-32 Neighboring gene DMAC1 pseudogene 1 Neighboring gene small nucleolar RNA, C/D box 115-33 Neighboring gene small nucleolar RNA, C/D box 115-34 Neighboring gene Prader Willi/Angelman region RNA 1 Neighboring gene small nucleolar RNA, C/D box 115-35 Neighboring gene small nucleolar RNA, C/D box 115-36 Neighboring gene small nucleolar RNA, C/D box 115-37 Neighboring gene small nucleolar RNA, C/D box 115-38 Neighboring gene small nucleolar RNA, C/D box 115-39 Neighboring gene small nucleolar RNA, C/D box 115-40 Neighboring gene small nucleolar RNA, C/D box 115-41 Neighboring gene imprinted in Prader-Willi syndrome Neighboring gene small nucleolar RNA, C/D box 115-43 Neighboring gene small nucleolar RNA, C/D box 115-42 Neighboring gene small nucleolar RNA, C/D box 115-44 Neighboring gene small nucleolar RNA, C/D box 115-45 Neighboring gene small nucleolar RNA, C/D box 115-46 Neighboring gene small nucleolar RNA, C/D box 115-47 Neighboring gene small nucleolar RNA, C/D box 115-48 Neighboring gene Prader Willi/Angelman region RNA 4 Neighboring gene small nucleolar RNA, C/D box 109B Neighboring gene ubiquitin protein ligase E3A Neighboring gene long intergenic non-protein coding RNA 2250 Neighboring gene uncharacterized LOC107984789 Neighboring gene ATPase phospholipid transporting 10A (putative) Neighboring gene RNA, 5S ribosomal pseudogene 390

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Other Names

  • UBE3A antisense RNA 1 (non-protein coding)
  • UBE3A antisense transcript
  • large noncoding antisense transcript
  • small nucleolar RNA host gene 14 (non-protein coding)

Clone Names

  • DKFZp762N022, DKFZp686C0927, DKFZp686M12165

Gene Ontology Provided by GOA

Process Evidence Code Pubs
RNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleolus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_002690.1 

    Range
    42698..638553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_146177.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC090983, AC124303, AC124312, AC124997, AF319524, AF400485, AF400486, AF400487, AF400490, AF400491, AF400492, AF400497, AF400498, AF400499, AF400501, AF400502, AY362864, AY362865, AY421730, BC080646, CN389953, DA296172, DN990150

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    24823608..25419462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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