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LOC102724428 salt inducible kinase 1B (putative) [ Homo sapiens (human) ]

Gene ID: 102724428, updated on 27-Nov-2021

Summary

Gene symbol
LOC102724428
Gene description
salt inducible kinase 1B (putative)
See related
Ensembl:ENSG00000275993
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SIK; SIK1; SIK-1; SIK1B; SNF1LK
Annotation information
Note: GeneID:102724428 is on a scaffold that is thought to be a false duplication and thus this gene is likely redundant with GeneID:150094. [11 Jun 2021]
Expression
Ubiquitous expression in adrenal (RPKM 33.0), liver (RPKM 26.8) and 25 other tissues See more
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Genomic context

See LOC102724428 in Genome Data Viewer
Location:
21p12
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 21 NC_000021.9 (6111131..6123778)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized CH507-42P11.6 Neighboring gene uncharacterized LOC107985506 Neighboring gene uncharacterized LOC107987288 Neighboring gene helicase SRCAP-like Neighboring gene uncharacterized LOC102724701 Neighboring gene uncharacterized LOC105379491

Genomic regions, transcripts, and products

Genomic Sequence:
NC_000021.9 Chromosome 21 Reference GRCh38.p13 Primary Assembly

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • FLJ00263, MGC33415

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine/threonine/tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular response to glucose starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
putative serine/threonine-protein kinase SIK1B; probable serine/threonine-protein kinase SIK1B
Names
Salt-inducible kinase 1
Serine/threonine-protein kinase SNF1-like kinase 1
Serine/threonine-protein kinase SNF1LK
salt-inducible kinase 1B
serine/threonine-protein kinase SIK1
NP_001307572.1
XP_016883697.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320643.3NP_001307572.1  putative serine/threonine-protein kinase SIK1B

    Status: VALIDATED

    Source sequence(s)
    AK131076, AW207331, BC038504, CU639417, HY023884
    Consensus CDS
    CCDS82645.1
    UniProtKB/Swiss-Prot
    P57059
    UniProtKB/TrEMBL
    A0A0B4J2F2
    Related
    ENSP00000482829.1, ENST00000613488.3
    Conserved Domains (2) summary
    cd14408
    Location:300349
    UBA_SIK1; UBA domain found in salt-inducible kinase 1 (SIK1)
    cd14071
    Location:26278
    STKc_SIK; Catalytic domain of the Serine/Threonine Kinases, Salt-Inducible kinases

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p13 Primary Assembly

    Range
    6111131..6123778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028208.1XP_016883697.1  probable serine/threonine-protein kinase SIK1B isoform X1

    Conserved Domains (1) summary
    cd14071
    Location:26278
    STKc_SIK; Catalytic domain of the Serine/Threonine Kinases, Salt-Inducible kinases
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