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DBT dihydrolipoamide branched chain transacylase E2 [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102357892, updated on 4-May-2024

Summary

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Gene symbol
DBT
Gene description
dihydrolipoamide branched chain transacylase E2
See related
Ensembl:ENSLACG00000013463
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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See DBT in Genome Data Viewer
Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 6 NC_088144.1 (62537934..62567107)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819578.1 (862074..892084, complement)

Chromosome 6 - NC_088144.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 14Ab Neighboring gene uncharacterized LOC135357643 Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene dynein light chain Tctex-type protein 2B Neighboring gene leucine rich repeat containing 39 Neighboring gene tRNA methyltransferase 13 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipoic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088144.1 Reference fLatCha1.pri

    Range
    62537934..62567107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006000022.3 → XP_006000084.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    H3B073
    Related
    ENSLACP00000015294.1
    Conserved Domains (4) summary
    cd06849
    Location:64 → 137
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:66 → 492
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:277 → 489
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:173 → 206
    E3_binding; e3 binding domain
Nucleotide Protein
Heading Accession and Version

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