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smg6 SMG6 nonsense mediated mRNA decay factor [ Haplochromis burtoni (Burton's mouthbrooder) ]

Gene ID: 102292757, updated on 10-Mar-2024

Summary

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Gene symbol
smg6
Gene description
SMG6 nonsense mediated mRNA decay factor
See related
Ensembl:ENSHBUG00000021311
Gene type
protein coding
RefSeq status
MODEL
Organism
Haplochromis burtoni
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Haplochromis
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
102 current NCSU_Asbu1 (GCF_018398535.1) Unplaced Scaffold NW_024582854.1 (114646..134550)
101 previous assembly AstBur1.0 (GCF_000239415.1) Unplaced Scaffold NW_005179909.1 (276818..296709, complement)

NW_024582854.1Genomic Context describing neighboring genes Neighboring gene OVCA2 serine hydrolase domain containing Neighboring gene uncharacterized LOC121812253 Neighboring gene TAO kinase 1b Neighboring gene protein ABHD15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
telomerase-binding protein EST1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haplochromis burtoni Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NCSU_Asbu1 Primary Assembly

Genomic

  1. NW_024582854.1 Reference NCSU_Asbu1 Primary Assembly

    Range
    114646..134550
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014329062.2 → XP_014184548.1  telomerase-binding protein EST1A isoform X1

    Conserved Domains (4) summary
    cd09885
    Location:1458 → 1644
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    sd00006
    Location:970 → 998
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:956 → 1316
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:837 → 946
    EST1; Telomerase activating protein Est1

  2. XM_005946800.2 → XP_005946862.1  telomerase-binding protein EST1A isoform X2

    UniProtKB/TrEMBL
    A0A3Q2X4C8
    Related
    ENSHBUP00000034032.1
    Conserved Domains (4) summary
    cd09885
    Location:1452 → 1638
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    sd00006
    Location:964 → 992
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:950 → 1310
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:837 → 940
    EST1; Telomerase activating protein Est1
Nucleotide Protein
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