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Ak6 adenylate kinase 6 [ Mus musculus (house mouse) ]

Gene ID: 102216272, updated on 10-Mar-2024

Summary

Official Symbol
Ak6provided by MGI
Official Full Name
adenylate kinase 6provided by MGI
Primary source
MGI:MGI:5510732
See related
Ensembl:ENSMUSG00000078941 AllianceGenome:MGI:5510732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AK/ATPase; 2810046E22Rik; 4921516M08Rik
Summary
Predicted to enable ATP binding activity and adenylate kinase activity. Predicted to be located in centrosome; cytosol; and nuclear body. Predicted to be active in cytoplasm and nucleus. Orthologous to human AK6 (adenylate kinase 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 45.2), CNS E11.5 (RPKM 27.6) and 19 other tissues See more
Orthologs
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Genomic context

Location:
13 D1; 13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (100787851..100802923)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (100651343..100666415)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene MARVEL (membrane-associating) domain containing 2 Neighboring gene predicted gene, 24261 Neighboring gene RAD17 checkpoint clamp loader component Neighboring gene STARR-positive B cell enhancer ABC_E7268 Neighboring gene TATA-box binding protein associated factor 9 Neighboring gene STARR-seq mESC enhancer starr_35476 Neighboring gene coiled-coil domain containing 125 Neighboring gene cyclin dependent kinase 7 Neighboring gene STARR-seq mESC enhancer starr_35477 Neighboring gene STARR-positive B cell enhancer ABC_E7269 Neighboring gene STARR-positive B cell enhancer mm9_chr13:101513935-101514236 Neighboring gene mitochondrial ribosomal protein S36

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Clone Names

  • MGC28404

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables adenylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables adenylate kinase activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Cajal body ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
adenylate kinase isoenzyme 6
Names
ATP-AMP transphosphorylase 6
coilin-interacting nuclear ATPase protein
dual activity adenylate kinase/ATPase
NP_081868.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027592.3NP_081868.1  adenylate kinase isoenzyme 6

    See identical proteins and their annotated locations for NP_081868.1

    Status: VALIDATED

    Source sequence(s)
    AC165159, AK014903
    Consensus CDS
    CCDS26734.1
    UniProtKB/Swiss-Prot
    Q8VCP8
    Related
    ENSMUSP00000022135.9, ENSMUST00000022135.15
    Conserved Domains (1) summary
    COG1936
    Location:4170
    Fap7; Broad-specificity NMP kinase [Nucleotide transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    100787851..100802923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)