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Dpyd dihydropyrimidine dehydrogenase [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101964470, updated on 8-Mar-2024

Summary

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Gene symbol
Dpyd
Gene description
dihydropyrimidine dehydrogenase
Locus tag
H1C71_034212
See related
EnsemblRapid:ENSSTOG00015005602
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024405058.1 (106508890..107287521, complement)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936537.1 (1660461..2439305)

NW_024405058.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120890836 Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene polypyrimidine tract binding protein 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120890839 Neighboring gene uncharacterized LOC120890838 Neighboring gene uncharacterized LOC120890842 Neighboring gene uncharacterized LOC120890840 Neighboring gene uncharacterized LOC120890841 Neighboring gene synaptojanin-1-like Neighboring gene uncharacterized LOC120890844

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dihydropyrimidine dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables uracil binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in thymine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in uracil catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydropyrimidine dehydrogenase [NADP(+)]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024405058.1 Reference HiC_Itri_2 Primary Assembly

    Range
    106508890..107287521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040289203.1 → XP_040145137.1  dihydropyrimidine dehydrogenase [NADP(+)]

    UniProtKB/TrEMBL
    I3MBM4
    Related
    ENSSTOP00015006816.1, ENSSTOT00015007520.1
    Conserved Domains (3) summary
    cd02940
    Location:478 → 780
    DHPD_FMN; Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and ...
    TIGR01944
    Location:869 → 951
    rnfB; electron transport complex, RnfABCDGE type, B subunit
    cl40752
    Location:53 → 459
    GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]
Nucleotide Protein
Heading Accession and Version

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