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Uros uroporphyrinogen III synthase [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101964253, updated on 8-Mar-2024

Summary

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Gene symbol
Uros
Gene description
uroporphyrinogen III synthase
Locus tag
H1C71_000165
See related
EnsemblRapid:ENSSTOG00015013838
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024407213.1 (11744646..11770000)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936486.1 (13792354..13816744, complement)

NW_024407213.1Genomic Context describing neighboring genes Neighboring gene fibronectin type III and ankyrin repeat domains 1 Neighboring gene DEAH-box helicase 32 (putative) Neighboring gene BRCA2 and CDKN1A interacting protein Neighboring gene matrix metallopeptidase 21 Neighboring gene erythroid differentiation regulatory factor 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables uroporphyrinogen-III synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in uroporphyrinogen III biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
uroporphyrinogen-III synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024407213.1 Reference HiC_Itri_2 Primary Assembly

    Range
    11744646..11770000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005320763.4 → XP_005320820.1  uroporphyrinogen-III synthase isoform X1

    UniProtKB/TrEMBL
    I3MI16
    Conserved Domains (1) summary
    cd06578
    Location:3 → 255
    HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...

  2. XM_013356603.3 → XP_013212057.1  uroporphyrinogen-III synthase isoform X2

    Conserved Domains (1) summary
    cd06578
    Location:3 → 228
    HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...

  3. XM_040272424.1 → XP_040128358.1  uroporphyrinogen-III synthase isoform X3

    Conserved Domains (1) summary
    cl03649
    Location:3 → 130
    HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...

  4. XM_040272422.1 → XP_040128356.1  uroporphyrinogen-III synthase isoform X1

    UniProtKB/TrEMBL
    I3MI16
    Related
    ENSSTOP00015016919.1, ENSSTOT00015018550.1
    Conserved Domains (1) summary
    cd06578
    Location:3 → 255
    HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...

  5. XM_040272423.1 → XP_040128357.1  uroporphyrinogen-III synthase isoform X2

    Conserved Domains (1) summary
    cd06578
    Location:3 → 228
    HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...
Nucleotide Protein
Heading Accession and Version

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