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PPP1R12B protein phosphatase 1 regulatory subunit 12B [ Felis catus (domestic cat) ]

Gene ID: 101098766, updated on 8-Mar-2024

Summary

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Official Symbol
PPP1R12B
Official Full Name
protein phosphatase 1 regulatory subunit 12B
Primary source
VGNC:VGNC:107924
See related
EnsemblRapid:ENSFCTG00005020008
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: F1
Exon count:
30
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) F1 NC_058384.1 (40840562..41054429)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) F1 NC_018739.3 (43066364..43282647)

Chromosome F1 - NC_058384.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109495698 Neighboring gene leucine rich repeat containing G protein-coupled receptor 6 Neighboring gene ubiquitin conjugating enzyme E2 T Neighboring gene uncharacterized LOC109495702 Neighboring gene synaptotagmin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111558397 Neighboring gene lysine demethylase 5B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables enzyme inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in A band IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 12B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058384.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    40840562..41054429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019821983.3 → XP_019677542.2  protein phosphatase 1 regulatory subunit 12B isoform X1

    UniProtKB/TrEMBL
    A0A337S3Q2
    Related
    ENSFCTP00005042959.1, ENSFCTT00005058494.1
    Conserved Domains (6) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:65 → 154
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:944 → 1050
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cd21944
    Location:669 → 725
    IPD_MYPT1; inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1(MYPT1)

  2. XM_019821984.3 → XP_019677543.2  protein phosphatase 1 regulatory subunit 12B isoform X2

    UniProtKB/TrEMBL
    A0A337S3Q2
    Conserved Domains (4) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    TIGR04211
    Location:953 → 1053
    SH3_and_anchor; SH3 domain protein
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]

  3. XM_045048676.1 → XP_044904611.1  protein phosphatase 1 regulatory subunit 12B isoform X4

    UniProtKB/TrEMBL
    A0A5F5Y2T4
    Conserved Domains (6) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:65 → 154
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:944 → 1043
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cd21944
    Location:669 → 725
    IPD_MYPT1; inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1(MYPT1)

  4. XM_045048677.1 → XP_044904612.1  protein phosphatase 1 regulatory subunit 12B isoform X8

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]

  5. XM_019821986.3 → XP_019677545.2  protein phosphatase 1 regulatory subunit 12B isoform X7

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]

  6. XM_019821985.3 → XP_019677544.2  protein phosphatase 1 regulatory subunit 12B isoform X3

    UniProtKB/TrEMBL
    A0A5F5Y2T4
    Related
    ENSFCTP00005042717.1, ENSFCTT00005058169.1
    Conserved Domains (6) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    pfam05109
    Location:532 → 825
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:65 → 154
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:944 → 1044
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cd21944
    Location:669 → 725
    IPD_MYPT1; inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1(MYPT1)

  7. XM_011290936.4 → XP_011289238.2  protein phosphatase 1 regulatory subunit 12B isoform X5

    UniProtKB/TrEMBL
    A0A5F5XRW5
    Conserved Domains (4) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:65 → 154
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:883 → 989
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

  8. XM_003999376.5 → XP_003999425.4  protein phosphatase 1 regulatory subunit 12B isoform X6

    UniProtKB/TrEMBL
    A0A5F5XRW5, A0A5F5Y2T4
    Related
    ENSFCTP00005042531.1, ENSFCTT00005057912.1
    Conserved Domains (4) summary
    PHA03095
    Location:61 → 290
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:90 → 121
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:65 → 154
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:883 → 983
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

  9. XM_011290940.3 → XP_011289242.1  protein phosphatase 1 regulatory subunit 12B isoform X9

    See identical proteins and their annotated locations for XP_011289242.1

    Conserved Domains (1) summary
    pfam15898
    Location:109 → 215
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

  10. XM_011290942.4 → XP_011289244.1  protein phosphatase 1 regulatory subunit 12B isoform X10

    UniProtKB/TrEMBL
    A0A2I2UK97
    Related
    ENSFCTP00005042231.1, ENSFCTT00005057492.1
    Conserved Domains (1) summary
    pfam15898
    Location:87 → 187
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

RNA

  1. XR_006591626.1 RNA Sequence

  2. XR_002739181.2 RNA Sequence

Nucleotide Protein
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