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sppl2 signal peptide peptidase-like 2 [ Takifugu rubripes (torafugu) ]

Gene ID: 101073861, updated on 8-Mar-2024

Summary

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Gene symbol
sppl2
Gene description
signal peptide peptidase-like 2
See related
Ensembl:ENSTRUG00000006665
Gene type
protein coding
RefSeq status
MODEL
Organism
Takifugu rubripes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu
Also known as
sppl2b
Orthologs
human zebrafish all
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Genomic context

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See sppl2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
15
Annotation release Status Assembly Chr Location
103 current fTakRub1.2 (GCF_901000725.2) 22 NC_042306.1 (4571323..4578295, complement)
101 previous assembly FUGU5 (GCF_000180615.1) 22 NC_018911.1 (3061650..3068595, complement)

Chromosome 22 - NC_042306.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing protein 16-like Neighboring gene rho/rac guanine nucleotide exchange factor (GEF) 18a Neighboring gene death-associated protein kinase 3 Neighboring gene polyhomeotic homolog 3 (Drosophila)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 2B
Names
signal peptide peptidase like 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Takifugu rubripes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fTakRub1.2 Primary Assembly

Genomic

  1. NC_042306.1 Reference fTakRub1.2 Primary Assembly

    Range
    4571323..4578295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003975382.3 → XP_003975431.2  signal peptide peptidase-like 2B

    UniProtKB/TrEMBL
    A0A674N5K3, H2SVE2
    Related
    ENSTRUP00000016380.3, ENSTRUT00000016452.3
    Conserved Domains (2) summary
    cd02129
    Location:37 → 156
    PA_hSPPL_like; Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the late endosomes, ...
    pfam04258
    Location:206 → 497
    Peptidase_A22B; Signal peptide peptidase

RNA

  1. XR_003886938.1 RNA Sequence

  2. XR_965480.2 RNA Sequence

    Related
    ENSTRUT00000086819.1
Nucleotide Protein
Heading Accession and Version

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