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mlh3 mutL homolog 3 (E. coli) [ Takifugu rubripes (torafugu) ]

Gene ID: 101068291, updated on 8-Mar-2024

Summary

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Gene symbol
mlh3
Gene description
mutL homolog 3 (E. coli)
See related
Ensembl:ENSTRUG00000018306
Gene type
protein coding
RefSeq status
MODEL
Organism
Takifugu rubripes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu
Orthologs
human zebrafish all
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Genomic context

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See mlh3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
103 current fTakRub1.2 (GCF_901000725.2) 2 NC_042286.1 (9580242..9586129)
101 previous assembly FUGU5 (GCF_000180615.1) 2 NC_018891.1 (7508299..7513719)

Chromosome 2 - NC_042286.1Genomic Context describing neighboring genes Neighboring gene NIMA related kinase 9 Neighboring gene uncharacterized LOC115248162 Neighboring gene transmembrane p24 trafficking protein 10 Neighboring gene v-fos FBJ murine osteosarcoma viral oncogene homolog Aa Neighboring gene Jun dimerization protein 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA mismatch repair protein Mlh3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Takifugu rubripes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fTakRub1.2 Primary Assembly

Genomic

  1. NC_042286.1 Reference fTakRub1.2 Primary Assembly

    Range
    9580242..9586129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029831770.1 → XP_029687630.1  DNA mismatch repair protein Mlh3 isoform X2

    UniProtKB/TrEMBL
    H2VC90
    Related
    ENSTRUP00000046833.3, ENSTRUT00000046991.3
    Conserved Domains (3) summary
    smart00853
    Location:851 → 1032
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:211 → 350
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cl00075
    Location:12 → 195
    HATPase; Histidine kinase-like ATPase domain

  2. XM_011616961.2 → XP_011615263.1  DNA mismatch repair protein Mlh3 isoform X1

    Conserved Domains (3) summary
    smart00853
    Location:885 → 1066
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:211 → 350
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cl00075
    Location:12 → 195
    HATPase; Histidine kinase-like ATPase domain

RNA

  1. XR_965527.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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