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Sec61bl SEC61 translocon subunit beta like [ Mus musculus (house mouse) ]

Gene ID: 101055909, updated on 2-Nov-2024

Summary

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Official Symbol
Sec61blprovided by MGI
Official Full Name
SEC61 translocon subunit beta likeprovided by MGI
Primary source
MGI:MGI:3642323
See related
AllianceGenome:MGI:3642323
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10320
Summary
Predicted to enable epidermal growth factor binding activity; guanyl-nucleotide exchange factor activity; and ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation; post-translational protein targeting to membrane, translocation; and retrograde protein transport, ER to cytosol. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum quality control compartment. Predicted to be part of Sec61 translocon complex. Predicted to be active in membrane. Orthologous to human SEC61B (SEC61 translocon subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Sec61bl in Genome Data Viewer
Location:
13 D1; 13 52.06 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (98625867..98626349, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (98489533..98489841, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_35422 Neighboring gene RIKEN cDNA 2310005E17 gene Neighboring gene predicted gene, 46437 Neighboring gene predicted gene, 52050 Neighboring gene STARR-seq mESC enhancer starr_35424 Neighboring gene STARR-positive B cell enhancer mm9_chr13:99265550-99265851 Neighboring gene STARR-seq mESC enhancer starr_35425 Neighboring gene predicted gene, 41032 Neighboring gene STARR-seq mESC enhancer starr_35427 Neighboring gene predicted gene, 41033 Neighboring gene predicted gene, 48049

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables epidermal growth factor binding ISO
Inferred from Sequence Orthology
more info
  
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in ERAD pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in SRP-dependent cotranslational protein targeting to membrane, translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in post-translational protein targeting to membrane, translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde protein transport, ER to cytosol ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of Sec61 translocon complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum quality control compartment ISO
Inferred from Sequence Orthology
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein transport protein Sec61 subunit beta-like
Names
predicted pseudogene 10320
protein transport protein Sec61 subunit beta pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    98625867..98626349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158243.1 → XP_036014136.1  protein transport protein Sec61 subunit beta-like

    Conserved Domains (1) summary
    pfam03911
    Location:60 → 97
    Sec61_beta; Sec61beta family
Nucleotide Protein
Heading Accession and Version

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