U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DNM3OS DNM3 opposite strand/antisense RNA [ Homo sapiens (human) ]

Gene ID: 100628315, updated on 10-Dec-2024

Summary

Official Symbol
DNM3OSprovided by HGNC
Official Full Name
DNM3 opposite strand/antisense RNAprovided by HGNC
Primary source
HGNC:HGNC:41228
See related
AllianceGenome:HGNC:41228
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DNM3-AS1; MIR199A2HG
Summary
Enables miRNA inhibitor activity via base-pairing. Involved in cellular response to transforming growth factor beta stimulus; positive regulation of miRNA catabolic process; and regulation of gene expression. Predicted to be part of RISC complex. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in ovary (RPKM 8.5), endometrium (RPKM 7.1) and 20 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See DNM3OS in Genome Data Viewer
Location:
1q24.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (172136879..172144835, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (171493599..171501554, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (172106019..172113975, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1551 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2086 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:171840934-171841454 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2087 Neighboring gene DNM3 intronic transcript 1 Neighboring gene MPRA-validated peak455 silencer Neighboring gene dynamin 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:171911601-171912102 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:171935008-171935684 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:171935685-171936361 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:171952925-171953114 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:172025253-172025838 Neighboring gene microRNA 199a-2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2088 Neighboring gene microRNA 3120 Neighboring gene microRNA 214 Neighboring gene MPRA-validated peak456 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:172247487-172248141 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:172300102-172300228 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2089 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2090 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:172329514-172330140 Neighboring gene RNA, U6 small nuclear 157, pseudogene Neighboring gene uncharacterized LOC102724528 Neighboring gene chromosome 1 open reading frame 105

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Other Names

  • DNM3 antisense RNA 1 (non-protein coding)
  • DNM3 opposite strand/antisense RNA (non-protein coding)
  • MIR199A2 host gene (non-protein coding)
  • dynamin 3, opposite strand

Clone Names

  • FLJ11481

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038397.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AL137157, AU311708, FJ623959
  2. NR_103486.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks three alternate segments, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AL137157, AU311708, DB261523, FJ623959

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    172136879..172144835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    171493599..171501554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)