DHCR24 24-dehydrocholesterol reductase [Sus scrofa (pig)] - Gene

Summary

Gene symbol: DHCR24
Gene description: 24-dehydrocholesterol reductase
See related: Ensembl:ENSSSCG00000027525
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in liver (RPKM 105.1), mixtures (RPKM 47.1) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	6	NC_010448.4 (157483794..157519060)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	6	NC_010448.3 (145547688..145582947)

Chromosome 6 - NC_010448.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables FAD binding	IEA Inferred from Electronic Annotation more info	PubMed
enables delta24(24-1) sterol reductase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in steroid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: delta(24)-sterol reductase

NP_001230283.1

EC 1.3.1.-

EC 1.3.1.72

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243354.1 → NP_001230283.1 delta(24)-sterol reductase

Status: VALIDATED

Source sequence(s)

BM484839, BP152852, DB782678, DN103713, DY413258, FP326650

UniProtKB/TrEMBL

A0A480JQE4, A0A4X1WB17, A0A8D1KAM6

Related

ENSSSCP00000025201.2, ENSSSCT00000027336.4

Conserved Domains (2) summary

COG0277
Location:114 → 239

GlcD; FAD/FMN-containing dehydrogenase [Energy production and conversion]

pfam01565
Location:114 → 203

FAD_binding_4; FAD binding domain