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MAP3K4 mitogen-activated protein kinase kinase kinase 4 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100602313, updated on 8-Mar-2024

Summary

Gene symbol
MAP3K4
Gene description
mitogen-activated protein kinase kinase kinase 4
See related
EnsemblRapid:ENSNLEG00000011428
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
29
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 3 NC_044383.1 (146734158..146860646)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 3 NC_019818.1 (148433894..148570559)

Chromosome 3 - NC_044383.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 3 Neighboring gene uncharacterized LOC115834475 Neighboring gene plasminogen Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 4 Neighboring gene parkin RBR E3 ubiquitin protein ligase Neighboring gene keratin, type II cytoskeletal 8 pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of stress-activated MAPK cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
mitogen-activated protein kinase kinase kinase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044383.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    146734158..146860646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030809934.1XP_030665794.1  mitogen-activated protein kinase kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    A0A2I3GTY3
    Related
    ENSNLEP00000013924.3, ENSNLET00000014607.4
    Conserved Domains (1) summary
    cd06626
    Location:13411600
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4
  2. XM_030809936.1XP_030665796.1  mitogen-activated protein kinase kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    A0A2I3GU03
    Related
    ENSNLEP00000034717.2, ENSNLET00000043947.2
    Conserved Domains (1) summary
    cd06626
    Location:12931552
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4
  3. XM_030809935.1XP_030665795.1  mitogen-activated protein kinase kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    A0A2I3GTY3
    Conserved Domains (1) summary
    cd06626
    Location:13371596
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4
  4. XM_030809937.1XP_030665797.1  mitogen-activated protein kinase kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    A0A2I3GU03
    Conserved Domains (1) summary
    cd06626
    Location:12891548
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4
  5. XM_030809938.1XP_030665798.1  mitogen-activated protein kinase kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    A0A2I3GG90
    Conserved Domains (1) summary
    cl21453
    Location:13411414
    PKc_like; Protein Kinases, catalytic domain
  6. XM_030809939.1XP_030665799.1  mitogen-activated protein kinase kinase kinase 4 isoform X6

    Conserved Domains (1) summary
    cd06626
    Location:7931052
    STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4

RNA

  1. XR_004029408.1 RNA Sequence