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POLA1 DNA polymerase alpha 1, catalytic subunit [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100599551, updated on 8-Mar-2024

Summary

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Gene symbol
POLA1
Gene description
DNA polymerase alpha 1, catalytic subunit
See related
EnsemblRapid:ENSNLEG00000010066
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
37
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) X NC_044406.1 (23223735..23526371)
102 previous assembly Nleu_3.0 (GCF_000146795.2) X NC_019841.1 (22779890..23085266)

Chromosome X - NC_044406.1Genomic Context describing neighboring genes Neighboring gene phosphate cytidylyltransferase 1B, choline Neighboring gene 60S ribosomal protein L23 pseudogene Neighboring gene small Cajal body-specific RNA 24 Neighboring gene platelet-activating factor acetylhydrolase IB subunit beta pseudogene Neighboring gene aristaless related homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables purine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyrimidine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lagging strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leading strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase alpha catalytic subunit
Names
polymerase (DNA directed), alpha 1, catalytic subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044406.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    23223735..23526371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030807188.1 → XP_030663048.1  DNA polymerase alpha catalytic subunit isoform X2

    UniProtKB/TrEMBL
    G1RGE5
    Related
    ENSNLEP00000030235.2, ENSNLET00000038284.2
    Conserved Domains (2) summary
    TIGR00592
    Location:1 → 1089
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1129 → 1319
    zf-DNA_Pol; DNA Polymerase alpha zinc finger

  2. XM_030807187.1 → XP_030663047.1  DNA polymerase alpha catalytic subunit isoform X1

    UniProtKB/TrEMBL
    G1RGE5
    Related
    ENSNLEP00000012295.3, ENSNLET00000012893.4
    Conserved Domains (2) summary
    TIGR00592
    Location:56 → 1231
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1271 → 1461
    zf-DNA_Pol; DNA Polymerase alpha zinc finger
Nucleotide Protein
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