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PTRH2 peptidyl-tRNA hydrolase 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100597061, updated on 8-Mar-2024

Summary

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Gene symbol
PTRH2
Gene description
peptidyl-tRNA hydrolase 2
See related
EnsemblRapid:ENSNLEG00000000792 EnsemblRapid:ENSNLEG00000039302
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 14 NC_044394.1 (11517290..11527775)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 14 NC_019829.1 (10331390..10341874, complement)

Chromosome 14 - NC_044394.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene vacuole membrane protein 1 Neighboring gene clathrin heavy chain Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene DEAH-box helicase 40

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aminoacyl-tRNA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of anoikis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of anoikis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptidyl-tRNA hydrolase 2, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044394.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    11517290..11527775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003278487.4 → XP_003278535.2  peptidyl-tRNA hydrolase 2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    G1QJ28
    Related
    ENSNLEP00000000922.3, ENSNLET00000000980.3
    Conserved Domains (1) summary
    cd02430
    Location:65 → 179
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

  2. XM_030828389.1 → XP_030684249.1  peptidyl-tRNA hydrolase 2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    G1QJ28
    Conserved Domains (1) summary
    cd02430
    Location:65 → 179
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

  3. XM_030828388.1 → XP_030684248.1  peptidyl-tRNA hydrolase 2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    G1QJ28
    Conserved Domains (1) summary
    cd02430
    Location:66 → 180
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

  4. XM_030828387.1 → XP_030684247.1  peptidyl-tRNA hydrolase 2, mitochondrial isoform X1

    Related
    ENSNLEP00000055218.1, ENSNLET00000067224.1
    Conserved Domains (2) summary
    pfam03221
    Location:87 → 156
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:16 → 63
    HTH; Helix-turn-helix domains
Nucleotide Protein
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