U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ABHD14A-ACY1 ABHD14A-ACY1 readthrough [ Homo sapiens (human) ]

Gene ID: 100526760, updated on 13-May-2022

Summary

Official Symbol
ABHD14A-ACY1provided by HGNC
Official Full Name
ABHD14A-ACY1 readthroughprovided by HGNC
Primary source
HGNC:HGNC:38856
See related
Ensembl:ENSG00000114786 AllianceGenome:HGNC:38856
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus represents naturally occurring read-through transcription between the neighboring abhydrolase domain containing 14A (ABHD14A) and aminoacylase 1 (ACY1) genes on chromosome 3. The read-through transcript encodes a protein that shares sequence identity with the downstream gene product but its N-terminal region is distinct due to the use of an alternate start codon relative to the upstream gene. [provided by RefSeq, Oct 2015]
Expression
Biased expression in kidney (RPKM 192.8), duodenum (RPKM 69.0) and 7 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ABHD14A-ACY1 in Genome Data Viewer
Location:
3p21.2
Exon count:
17
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (51975064..51989197)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (52007983..52022117)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (52009080..52023213)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 62 Neighboring gene poly(rC) binding protein 4 Neighboring gene abhydrolase domain containing 14B Neighboring gene Sharpr-MPRA regulatory region 207 Neighboring gene abhydrolase domain containing 14A Neighboring gene aminoacylase 1 Neighboring gene ribosomal protein L29 Neighboring gene Sharpr-MPRA regulatory region 12856

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ60317, FLJ60467

General protein information

Preferred Names
ABHD14A-ACY1 readthrough (NMD candidate)
Names
ABHD14A-ACY1 readthrough (non-protein coding)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001316331.2NP_001303260.1  ABHD14A-ACY1 readthrough (NMD candidate)

    Status: VALIDATED

    Source sequence(s)
    AC115284, AK298086
    UniProtKB/TrEMBL
    B4DNW0
    Related
    ENSP00000420487.1, ENST00000463937.1
    Conserved Domains (2) summary
    cd05646
    Location:99489
    M20_AcylaseI_like; M20 Aminoacylase-I like subfamily
    TIGR01880
    Location:91491
    Ac-peptdase-euk; N-acyl-L-amino-acid amidohydrolase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    51975064..51989197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    52007983..52022117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_037192.1: Suppressed sequence

    Description
    NR_037192.1: This RefSeq was removed because it is now thought that this gene does encode a protein.