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fgd3 FYVE, RhoGEF and PH domain containing 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100490625, updated on 17-Aug-2024

Summary

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Official Symbol
fgd3provided by Xenbase
Official Full Name
FYVE, RhoGEF and PH domain containing 3provided by Xenbase
Primary source
Xenbase:XB-GENE-995891
See related
Ensembl:ENSXETG00000034175
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
zfyve5
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
20
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (150903024..150981882)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683495.1 (165174..238249, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 40 Neighboring gene bicaudal D homolog 2 Neighboring gene sushi domain containing 3 Neighboring gene caspase recruitment domain family member 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FYVE, RhoGEF and PH domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    150903024..150981882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004914180.4 → XP_004914237.2  FYVE, RhoGEF and PH domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6I8QX31, A0A8J0R3D3
    Related
    ENSXETP00000058649.3, ENSXETT00000062056.3
    Conserved Domains (4) summary
    cd13236
    Location:778 → 882
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd13387
    Location:538 → 645
    PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
    cd15740
    Location:696 → 751
    FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
    pfam00621
    Location:328 → 506
    RhoGEF; RhoGEF domain

  2. XM_012961791.3 → XP_012817245.2  FYVE, RhoGEF and PH domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A1B8Y3W3, A0A6I8S184
    Related
    ENSXETP00000090675.2, ENSXETT00000104464.2
    Conserved Domains (4) summary
    cd13236
    Location:637 → 741
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd13387
    Location:397 → 504
    PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
    cd15740
    Location:555 → 610
    FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
    pfam00621
    Location:187 → 365
    RhoGEF; RhoGEF domain

  3. XM_002941737.5 → XP_002941783.3  FYVE, RhoGEF and PH domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A1B8Y3W3, A0A6I8S184
    Conserved Domains (4) summary
    cd13236
    Location:637 → 741
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd13387
    Location:397 → 504
    PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
    cd15740
    Location:555 → 610
    FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
    pfam00621
    Location:187 → 365
    RhoGEF; RhoGEF domain
Nucleotide Protein Strain
Heading Accession and Version

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