U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NCF2 neutrophil cytosolic factor 2 [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100476832, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
NCF2
Gene description
neutrophil cytosolic factor 2
Locus tag
PANDA_013148
See related
Ensembl:ENSAMEG00000002420
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NCF2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
15
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 8 NC_048225.1 (86142806..86172040)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003218028.1 (661629..691220, complement)

Chromosome 8 - NC_048225.1Genomic Context describing neighboring genes Neighboring gene ral guanine nucleotide dissociation stimulator like 1 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene SMG7 nonsense mediated mRNA decay factor Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene uncharacterized LOC117803425

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neutrophil cytosol factor 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048225.1 Reference ASM200744v2 Primary Assembly

    Range
    86142806..86172040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002923881.4 → XP_002923927.1  neutrophil cytosol factor 2

    UniProtKB/TrEMBL
    A0A7N5JI51, G1L6U4
    Related
    ENSAMEP00000002610.2, ENSAMET00000002725.2
    Conserved Domains (6) summary
    cd06406
    Location:350 → 428
    PB1_P67; A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in ...
    cd11871
    Location:244 → 297
    SH3_p67phox_N; N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    cd12046
    Location:460 → 512
    SH3_p67phox_C; C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    sd00006
    Location:6 → 32
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:71 → 98
    TPR_1; Tetratricopeptide repeat
    pfam13424
    Location:38 → 102
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.