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Lrtm1 leucine-rich repeats and transmembrane domains 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100360666, updated on 17-Aug-2024

Summary

Symbol
Lrtm1provided by RGD
Full Name
leucine-rich repeats and transmembrane domains 1provided by RGD
Primary source
RGD:2321691
See related
AllianceGenome:RGD:2321691
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Orthologous to human LRTM1 (leucine rich repeats and transmembrane domains 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 23.6), Lung (RPKM 8.1) and 8 other tissues See more
Orthologs
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Genomic context

Location:
16p16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (4216947..4224447)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (4210343..4217843)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (4993728..5005110)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene Wnt family member 5A Neighboring gene ribosomal protein L5, pseudogene 1 Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 3 Neighboring gene uncharacterized LOC103693891 Neighboring gene ribosomal protein L7, pseudogene 11

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
leucine-rich repeat and transmembrane domain-containing protein 1; leucine-rich repeats and transmembrane domains 1
Names
leucine-rich repeat and transmembrane domain-containing protein 1-like
rCG42269-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    4216947..4224447
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095222.1XP_038951150.1  leucine-rich repeat and transmembrane domain-containing protein 1

    UniProtKB/TrEMBL
    A6KG60
    Conserved Domains (6) summary
    PRK15370
    Location:97237
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    smart00013
    Location:89118
    LRRNT; Leucine rich repeat N-terminal domain
    sd00031
    Location:120167
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:101119
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:190249
    LRR_8; Leucine rich repeat
    cl15307
    Location:248301
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain