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XRN1 5'-3' exoribonuclease 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100351589, updated on 8-Mar-2024

Summary

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Gene symbol
XRN1
Gene description
5'-3' exoribonuclease 1
See related
Ensembl:ENSOCUG00000001861
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
47
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 14 NC_067387.1 (36890664..37013641, complement)

Chromosome 14 - NC_067387.1Genomic Context describing neighboring genes Neighboring gene transcription factor Dp-2 Neighboring gene glycerol kinase 5 Neighboring gene uncharacterized LOC127493941 Neighboring gene ATR serine/threonine kinase Neighboring gene plastin 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067387.1 Chromosome 14 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' RNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in rRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5'-3' exoribonuclease 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067387.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    36890664..37013641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002716566.4 → XP_002716612.1  5'-3' exoribonuclease 1 isoform X5

    UniProtKB/TrEMBL
    G1SGA9
    Related
    ENSOCUP00000001608.4
    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  2. XM_002716567.4 → XP_002716613.1  5'-3' exoribonuclease 1 isoform X6

    UniProtKB/TrEMBL
    A0A5F9CTD8
    Related
    ENSOCUP00000036765.1
    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  3. XM_008266279.3 → XP_008264501.1  5'-3' exoribonuclease 1 isoform X4

    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  4. XM_008266278.3 → XP_008264500.1  5'-3' exoribonuclease 1 isoform X2

    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  5. XM_002716565.4 → XP_002716611.1  5'-3' exoribonuclease 1 isoform X3

    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  6. XM_008266277.3 → XP_008264499.1  5'-3' exoribonuclease 1 isoform X1

    UniProtKB/TrEMBL
    G1SGA9
    Conserved Domains (2) summary
    COG5049
    Location:1 → 733
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]
    pfam03159
    Location:1 → 226
    XRN_N; XRN 5'-3' exonuclease N-terminus

  7. XM_051859028.1 → XP_051714988.1  5'-3' exoribonuclease 1 isoform X8

  8. XM_051859027.1 → XP_051714987.1  5'-3' exoribonuclease 1 isoform X7

  9. XM_008266280.3 → XP_008264502.1  5'-3' exoribonuclease 1 isoform X9

    Conserved Domains (1) summary
    COG5049
    Location:1 → 480
    XRN1; 5'-3' exonuclease [Replication, recombination and repair]

  10. XM_051859029.1 → XP_051714989.1  5'-3' exoribonuclease 1 isoform X10

RNA

  1. XR_007924531.1 RNA Sequence

  2. XR_007924532.1 RNA Sequence

  3. XR_007924533.1 RNA Sequence

Nucleotide Protein
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