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MIR346 microRNA mir-346 [ Pan troglodytes (chimpanzee) ]

Gene ID: 100316462, updated on 25-Jul-2024

Summary

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Gene symbol
MIR346
Gene description
microRNA mir-346
See related
miRBase:MI0008631
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
ptr-mir-346
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR346 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (98454563..98454656, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (89075006..89075099, complement)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107966779 Neighboring gene glutamate ionotropic receptor delta type subunit 1 Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC104008236 Neighboring gene U6 spliceosomal RNA Neighboring gene WAPL cohesin release factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Computational identification of novel microRNA homologs in the chimpanzee genome. Baev V, et al. Comput Biol Chem, 2009 Feb. PMID 18760970
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 346

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_035763.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JAQQLN020000008

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    98454563..98454656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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