AGXT2 alanine--glyoxylate aminotransferase 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: AGXT2
Gene description: alanine--glyoxylate aminotransferase 2
Locus tag: CR201_G0011876
See related: Ensembl:ENSPPYG00000015392
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	4	NC_071989.2 (35219529..35264236, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	5	NC_071990.1 (35219547..35264254, complement)

Chromosome 4 - NC_071989.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH78189 (e-PCR)
- UniSTS:27177

D5S2573 (e-PCR)
- UniSTS:54105

SGC33361 (e-PCR)
- UniSTS:14984

RH99171 (e-PCR)
- UniSTS:90541

RH17937 (e-PCR)
- UniSTS:50880

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables alanine-glyoxylate transaminase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in L-alanine catabolic process, by transamination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glyoxylate catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alanine--glyoxylate aminotransferase 2, mitochondrial

Names: (R)-3-amino-2-methylpropionate--pyruvate transaminase; AGT 2; D-3-aminoisobutyrate-pyruvate aminotransferase; D-AIBAT; D-beta-aminoisobutyrate-pyruvate aminotransferase; beta-ALAAT II; beta-alanine-pyruvate aminotransferase

NP_001124677.1

EC 2.6.1.18

EC 2.6.1.40

EC 2.6.1.44

XP_024102372.2

EC 2.6.1.18

EC 2.6.1.40

EC 2.6.1.44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131205.2 → NP_001124677.1 alanine--glyoxylate aminotransferase 2, mitochondrial

See identical proteins and their annotated locations for NP_001124677.1

Status: PROVISIONAL

Source sequence(s)

CR857258

UniProtKB/Swiss-Prot

Q5RFA3

UniProtKB/TrEMBL

A0A2J8WB16, H2PFB4

Related

ENSPPYP00000017192.3, ENSPPYT00000017891.3

Conserved Domains (2) summary

cd00610
Location:70 → 505

OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...

COG0160
Location:65 → 508

GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_071989.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

35219529..35264236 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)