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CAPZB capping actin protein of muscle Z-line subunit beta [ Sus scrofa (pig) ]

Gene ID: 100134958, updated on 17-Aug-2024

Summary

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Official Symbol
CAPZBprovided by VGNC
Official Full Name
capping actin protein of muscle Z-line subunit betaprovided by VGNC
Primary source
VGNC:VGNC:86184
See related
Ensembl:ENSSSCG00000003493
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in spleen (RPKM 116.4), ovary (RPKM 91.4) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (77780682..77912653, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (71842816..71985460, complement)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene aldo-keto reductase family 7 member A2 Neighboring gene solute carrier family 66 member 1 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene mitochondrial contact site and cristae organizing system subunit 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Identification and characterization of a differentially expressed protein (CAPZB) in skeletal muscle between Meishan and Large White pigs. Wang L, et al. Gene, 2014 Jul 10. PMID 24792893
  2. Porcine muscle sensory attributes associate with major changes in gene networks involving CAPZB, ANKRD1, and CTBP2. Ponsuksili S, et al. Funct Integr Genomics, 2009 Nov. PMID 19597856
  3. Sequence characterization, polymorphism, and chromosomal localizations of the porcine CapZ genes. Yang E, et al. Biochem Genet, 2008 Feb. PMID 17939027
  4. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data presented in our study suggests that the CAPZB gene may be a candidate gene of meat production trait and provides useful information for further studies on its roles in porcine skeletal muscle.
    Title: Identification and characterization of a differentially expressed protein (CAPZB) in skeletal muscle between Meishan and Large White pigs.
  2. CAPZB, ANKRD1, and CTBP2 are promoted as candidate genes for meat quality that provide a link between signal pathways.
    Title: Porcine muscle sensory attributes associate with major changes in gene networks involving CAPZB, ANKRD1, and CTBP2.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in barbed-end actin filament capping IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of lamellipodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of F-actin capping protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-actin-capping protein subunit beta
Names
CP beta1
F-actin capping protein beta subunit
F-actin capping protein subunit beta 1
capZ beta
capping actin protein of muscle Z-line beta subunit
capping protein (actin filament) muscle Z-line, beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113444.2 → NP_001106915.1  F-actin-capping protein subunit beta

    See identical proteins and their annotated locations for NP_001106915.1

    Status: VALIDATED

    Source sequence(s)
    AEMK02000045
    UniProtKB/Swiss-Prot
    A0A286ZU64, A0PFK7, A9XFX6, F1SUN9
    UniProtKB/TrEMBL
    D2JYW3
    Related
    ENSSSCP00000048858.2, ENSSSCT00000060352.2
    Conserved Domains (1) summary
    pfam01115
    Location:11 → 239
    F_actin_cap_B; F-actin capping protein, beta subunit

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    77780682..77912653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005656029.3 → XP_005656086.1  F-actin-capping protein subunit beta isoform X2

    See identical proteins and their annotated locations for XP_005656086.1

    UniProtKB/TrEMBL
    A0A8D0PTP0, A0A8D1Q0S8, D2JYW4, F1SUN8
    Related
    ENSSSCP00000003793.3, ENSSSCT00000003881.5
    Conserved Domains (1) summary
    pfam01115
    Location:11 → 239
    F_actin_cap_B; F-actin capping protein, beta subunit

  2. XM_021093208.1 → XP_020948867.1  F-actin-capping protein subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A4X1W705, A0A8D1PRT3
    Conserved Domains (1) summary
    pfam01115
    Location:15 → 243
    F_actin_cap_B; F-actin capping protein, beta subunit

  3. XM_021093206.1 → XP_020948865.1  F-actin-capping protein subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A5G2RIJ3, A0A8D0PSV6, A0A8D1SML6
    Related
    ENSSSCP00000071422.2, ENSSSCT00000073462.2
    Conserved Domains (1) summary
    pfam01115
    Location:15 → 243
    F_actin_cap_B; F-actin capping protein, beta subunit
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0PFK7.2 GenPept UniProtKB/Swiss-Prot:A0PFK7

Gene LinkOut

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