U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100080287, updated on 30-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
CACNB4
Gene description
calcium voltage-gated channel auxiliary subunit beta 4
See related
Ensembl:ENSOANG00000006106
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Also known as
CACNB4_tv1
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
19
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 9 NC_041736.1 (6498474..6613649, complement)

Chromosome 9 - NC_041736.1Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene nebulin Neighboring gene small nucleolar RNA SNORA7 Neighboring gene ARF like GTPase 5A Neighboring gene uncharacterized LOC114814259 Neighboring gene signal transducing adaptor molecule 2 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene formin like 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_041736.1 Chromosome 9 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Ca2+ channel-independent requirement for MAGUK family CACNB4 genes in initiation of zebrafish epiboly. Ebert AM, et al. Proc Natl Acad Sci U S A, 2008 Jan 8. PMID 18172207, Free PMC Article
  2. Genomic organization, expression, and phylogenetic analysis of Ca2+ channel beta4 genes in 13 vertebrate species. Ebert AM, et al. Physiol Genomics, 2008 Oct 8. PMID 18682574, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuromuscular junction development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
voltage-dependent L-type calcium channel subunit beta-4
Names
calcium channel, voltage-dependent, beta 4 subunit
voltage-gated calcium channel beta 4 subunit
voltage-gated calcium channel beta 4a subunit

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246852.1 → NP_001233781.1  voltage-dependent L-type calcium channel subunit beta-4

    See identical proteins and their annotated locations for NP_001233781.1

    Status: PROVISIONAL

    Source sequence(s)
    BK006591
    UniProtKB/TrEMBL
    A0A6I8NG51, B6IDG4
    Related
    ENSOANP00000041713.1, ENSOANT00000067602.1
    Conserved Domains (4) summary
    cd12043
    Location:57 → 124
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:184 → 364
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 57
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:194 → 365
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041736.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    6498474..6613649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007671115.4 → XP_007669305.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A6I8NG51, A0A6I8P1X2
    Related
    ENSOANP00000047032.1
    Conserved Domains (4) summary
    cd12043
    Location:97 → 164
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:224 → 404
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:56 → 97
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:234 → 405
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. XM_029071461.1 → XP_028927294.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X4

    UniProtKB/TrEMBL
    A0A6I8NG51
    Conserved Domains (3) summary
    cd12043
    Location:73 → 140
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:201 → 317
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:32 → 73
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  3. XM_007671116.2 → XP_007669306.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A6I8N9C0, A0A6I8NG51
    Related
    ENSOANP00000037732.1, ENSOANT00000069045.1
    Conserved Domains (4) summary
    cd12043
    Location:73 → 140
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:200 → 380
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:32 → 73
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:210 → 381
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  4. XM_029071458.2 → XP_028927291.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A6I8NG51, F6WUN2
    Related
    ENSOANP00000009737.2
    Conserved Domains (3) summary
    cd12043
    Location:44 → 111
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:171 → 351
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 44
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  5. XM_029071457.2 → XP_028927290.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A6I8NG51, F6WUN2
    Conserved Domains (3) summary
    cd12043
    Location:44 → 111
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:171 → 351
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 44
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  6. XM_029071460.2 → XP_028927293.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A6I8NG51, F6WUN2
    Conserved Domains (3) summary
    cd12043
    Location:44 → 111
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:171 → 351
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 44
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  7. XM_029071459.2 → XP_028927292.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A6I8NG51, F6WUN2
    Conserved Domains (3) summary
    cd12043
    Location:44 → 111
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:171 → 351
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 44
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.