CACNA1S calcium voltage-gated channel subunit alpha1 S [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: CACNA1S
Gene description: calcium voltage-gated channel subunit alpha1 S
See related: Ensembl:ENSOCUG00000003619
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: DHPR
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 44

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	16	NC_067389.1 (15148385..15206536, complement)

Chromosome 16 - NC_067389.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_067389.1 Chromosome 16 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables high voltage-gated calcium channel activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in calcium ion import across plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of voltage-gated calcium channel complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: voltage-dependent L-type calcium channel subunit alpha-1S

Names: calcium channel, voltage-dependent, L type, alpha 1S subunit; dihydropyridine receptor alpha-1S subunit; voltage-gated calcium channel subunit alpha Cav1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101720.1 → NP_001095190.1 voltage-dependent L-type calcium channel subunit alpha-1S

See identical proteins and their annotated locations for NP_001095190.1

Status: PROVISIONAL

Source sequence(s)

X05921

UniProtKB/Swiss-Prot

P07293

UniProtKB/TrEMBL

G1U2Z6

Related

ENSOCUP00000023753.2, ENSOCUT00000026489.2

Conserved Domains (4) summary

pfam00520
Location:1117 → 1392

Ion_trans; Ion transport protein

pfam08763
Location:1465 → 1536

Ca_chan_IQ; Voltage gated calcium channel IQ domain

pfam16885
Location:1706 → 1833

CAC1F_C; Voltage-gated calcium channel subunit alpha, C-term

pfam16905
Location:1401 → 1454

GPHH; Voltage-dependent L-type calcium channel, IQ-associated