2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.
Feature 1:substrate binding site [chemical binding site]
Evidence:
Structure:1V1A_A: binds KDG, defined using 3.5 A contacts - View structure with Cn3D
Comment:KDG can form several isomers in solution: open chain, alpha- or beta-pyranose, alpha- or beta-furanose. Structure indicates either the open chain keto form or alpha-furanose forms can be incorporated.
Jiyao W et al.(2023). "The conserved domain database in 2023.",