6KIX: Cryo-EM structure of human MLL1-NCP complex, binding mode1

PDB ID: 6KIXDownload
MMDB ID: 179294
PDB Deposition Date: 2019/7/20
Updated in MMDB: 2019/11
Experimental Method:
electron microscopy
Resolution: 4.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6KIX: 14-meric; determined by author
Molecular Components in 6KIX
Label Count Molecule
Proteins (12 molecules)
2
Histone H3
Molecule annotation
2
Histone H4
Molecule annotation
2
Histone H2A
Molecule annotation
2
Histone H2B 1.1
Molecule annotation
1
Retinoblastoma-binding Protein 5
Molecule annotation
1
Histone-lysine N-methyltransferase 2A
Molecule annotation
1
WD Repeat-containing Protein 5
Molecule annotation
1
Set1/ash2 Histone Methyltransferase Complex Subunit Ash2
Molecule annotation
Nucleotides(2 molecules)
1
DNA (145-mer)
Molecule annotation
1
DNA (145-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
ZINC IONZINC ION
3
1
LYSINELYSINE
4
1
GLUTAMINEGLUTAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303