6GR9: Human AURKC INCENP complex bound to VX-680

PDB ID: 6GR9Download
MMDB ID: 175359
PDB Deposition Date: 2018/6/10
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6GR9: dimeric; determined by author and by software (PISA)
Molecular Components in 6GR9
Label Count Molecule
Proteins (2 molecules)
1
Aurora Kinase C
(Gene symbol: AURKC)
Molecule annotation
1
Inner Centromere Protein
(Gene symbol: INCENP)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDECYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303